Esrrb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Esrrb
estrogen related receptor, beta
MGI:1346832

37 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Esrrb^tm1.1Nat/Esrrb^tm1.1Nat Tg(Myh6-cre)2182Mds/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * FVB/N	abnormal myocardial fiber physiology	J:241078
	abnormal sarcomere morphology	J:241078
	cardiac fibrosis	J:241078
	congestive heart failure	J:241078
	decreased calcium uptake by cardiac muscle	J:241078
	decreased cardiac muscle contractility	J:241078
	decreased ventricle muscle contractility	J:241078
	dilated cardiomyopathy	J:241078
	dilated heart left ventricle	J:241078
	enlarged heart	J:241078
	increased calcium uptake by cardiac muscle	J:241078
	premature death	J:241078
Esrrb^tm1.1Nat/Esrrb^tm1.2Nat Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL	abnormal scala media morphology	J:124941
	abnormal semicircular canal ampulla morphology	J:124941
	abnormal semicircular canal morphology	J:124941
	absent startle reflex	J:124941
	circling	J:124941
	decreased endolymph production	J:124941
	head bobbing	J:124941
	increased or absent threshold for auditory brainstem response	J:124941
	small scala media	J:124941
Esrrb^tm1.1Nat/Esrrb^tm1.2Nat Tg(Nes-cre)1Kln/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	absent strial marginal cells	J:124941
	increased or absent threshold for auditory brainstem response	J:124941
Esrrb^tm1.2Nat/Esrrb^tm1.2Nat involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL	prenatal lethality, complete penetrance	J:124941
Esrrb^tm1Vgi/Esrrb^tm1Vgi involves: 129S1/Sv * 129X1/SvJ	abnormal chorion morphology	J:42488
	abnormal extraembryonic tissue morphology	J:42488
	abnormal placenta morphology	J:42488
	abnormal trophoblast giant cell morphology	J:42488
	abnormal trophoblast layer morphology	J:42488
	absent chorion	J:42488
	absent placental labyrinth	J:42488
	absent spongiotrophoblast	J:42488
	decreased embryo size	J:42488
	decreased trophoblast giant cell number	J:42488
	disorganized embryonic tissue	J:42488
	embryonic growth retardation	J:42488
	embryonic lethality during organogenesis, complete penetrance	J:42488
	failure of chorioallantoic fusion	J:42488

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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