Creg1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Creg1
cellular repressor of E1A-stimulated genes 1
MGI:1344382

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Creg1^em1Yal/Creg1^em1Yal Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	abnormal circulating enzyme level	J:263073
	abnormal glucose homeostasis	J:263073
	abnormal lipid homeostasis	J:263073
	decreased glycogen level	J:263073
	decreased susceptibility to diet-induced hepatic steatosis	J:263073
	impaired glucose tolerance	J:263073
	increased body weight	J:263073
	increased circulating alanine transaminase level	J:263073
	increased circulating alkaline phosphatase level	J:263073
	increased circulating aspartate transaminase level	J:263073
	increased circulating insulin level	J:263073
	increased fasting circulating glucose level	J:263073
	increased liver cholesterol level	J:263073
	increased liver free fatty acids level	J:263073
	increased liver weight	J:263073
	insulin resistance	J:263073
Creg1^tm1Yal/Creg1⁺ involves: 129 * C57BL/6	abnormal autophagy	J:253911
	abnormal physiological neovascularization	J:262697
	decreased ventricle muscle contractility	J:253911
	increased cardiomyocyte apoptosis	J:253911
	increased myocardial infarct size	J:253911
	increased response of heart to induced stress	J:253911

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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