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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Parp2
poly (ADP-ribose) polymerase family, member 2
MGI:1341112
16 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Parp2tm1.1Shzh/Parp2tm1.1Shzh
Not Specified 		anemia J:358182
decreased DNA replication J:358182
decreased erythroblast number J:358182
embryonic lethality during organogenesis, complete penetrance J:358182
impaired hematopoiesis J:358182
liver hypoplasia J:358182
pale liver J:358182
spontaneous chromosome breakage J:358182
Parp2tm1Jmdm/Parp2tm1Jmdm
involves: 129S2/SvPas * C57BL/6 		abnormal cell cycle checkpoint function J:83371
normal cellular phenotype J:83371
elevated level of mitotic sister chromatid exchange J:83371
impaired DNA repair J:83371
increased cellular sensitivity to gamma-irradiation induced cell death J:83371
increased mortality induced by gamma-irradiation J:83371
induced chromosome breakage J:83371
normal neoplasm J:83371
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory