Mmp13 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp13
matrix metallopeptidase 13
MGI:1340026

14 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp13^{em1(IMPC)Ccpcz}/Mmp13^{em1(IMPC)Ccpcz} C57BL/6NCrl-Mmp13^{em1(IMPC)Ccpcz}/Ccpcz	short tibia	J:211773
Mmp13^tm1.1Werb/Mmp13^tm1.1Werb involves: 129S2/SvPas	abnormal trabecular bone morphology	J:94460
Mmp13^tm1.1Werb/Mmp13^tm1.1Werb involves: 129S2/SvPas	increased width of hypertrophic chondrocyte zone	J:94460
Mmp13^tm1Jdar/Mmp13^tm1Jdar B6.129S-Mmp13^tm1Jdar	decreased angiogenesis	J:150790
	decreased cell proliferation	J:150790
	delayed wound healing	J:150790
Mmp13^tm1Jdar/Mmp13^tm1Jdar involves: 129S/SvEv * C57BL/6J	abnormal bone healing	J:120352
	abnormal cartilage development	J:120352
	decreased angiogenesis	J:120352
Mmp13^tm1Smk/Mmp13^tm1Smk involves: 129S4/SvJae * C57BL/6	abnormal long bone hypertrophic chondrocyte zone	J:94723
	delayed bone ossification	J:94723
	increased long bone epiphyseal plate size	J:94723
	increased trabecular bone mass	J:94723
	short femur	J:94723
Mmp13^tm1Werb/Mmp13^tm1Werb Tg(CMV-cre)1Cgn/0 involves: 129S2/SvPas * BALB/cJ * C57BL/6	normal integument phenotype	J:104953
Mmp13^tm1Werb/Mmp13^tm1Werb Tg(Col1a1-cre)1Kry/0 involves: 129S2/SvPas	abnormal trabecular bone morphology	J:94460
Mmp13^tm1Werb/Mmp13^tm1Werb Tg(Col2a1-cre)1Rsjo/0 involves: 129S2/SvPas	abnormal trabecular bone morphology	J:94460
	increased width of hypertrophic chondrocyte zone	J:94460

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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