P2rx7 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

P2rx7
purinergic receptor P2X, ligand-gated ion channel, 7
MGI:1339957

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Enpp3^tm1Ktak/Enpp3^tm1Ktak P2rx7^tm1Gab/P2rx7^tm1Gab either: (involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6) or (involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6)	normal immune system phenotype	J:223825
	increased basophil cell number	J:223825
	increased mast cell number	J:223825
P2rx7^{tm1.1(P2RX7)Jde}/P2rx7^{tm2.1(P2RX7)Jde} involves: 129S2/SvPas C57BL/6J	abnormal cell physiology	J:251657
	abnormal non-rapid eye movement sleep pattern	J:251657
	abnormal sleep behavior	J:251657
	abnormal slow-wave sleep pattern	J:251657
	normal behavior/neurological phenotype	J:251657
	fragmentation of sleep/wake states	J:251657
	increased frequency of paradoxical sleep	J:251657

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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