Csf1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Csf1
colony stimulating factor 1 (macrophage)
MGI:1339753

38 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Csf1^op/Csf1^op involves: 129P2/OlaHsd * C3HeB/Fe * C57BL/6	decreased susceptibility to atherosclerosis	J:40136
	increased circulating cholesterol level	J:40136
Csf1^op/Csf1^op Csf2^tm1Ard/Csf2^tm1Ard involves: 129P2/OlaHsd * C57BL/6	abnormal bone marrow morphology	J:19089
	abnormal pulmonary alveolus morphology	J:19089
	absent teeth	J:19089
	decreased leukocyte cell number	J:19089
	extramedullary hematopoiesis	J:19089
	increased hemoglobin content	J:19089
	increased neutrophil cell number	J:19089
	interstitial pneumonia	J:19089
	lung inflammation	J:19089
	osteopetrosis	J:19089
	polycythemia	J:19089
	premature death	J:19089
	pulmonary alveolar proteinosis	J:19089
Csf1^op/Csf1^op Galc^twi/Galc^twi involves: C3HeB/Fe * C57BL/6J * CE/J	abnormal forebrain morphology	J:170081
	abnormal oligodendrocyte morphology	J:170081
	abnormal oligodendrocyte physiology	J:170081
	absent incisors	J:170081
	decreased body size	J:170081
	decreased oligodendrocyte number	J:170081
	decreased oligodendrocyte progenitor number	J:170081
	demyelination	J:170081
	domed cranium	J:170081
	hindlimb paralysis	J:170081
	impaired macrophage chemotaxis	J:170081
	premature death	J:170081
	tremors	J:170081
	weight loss	J:170081
Csf1^op/Csf1^op Mpz^tm1Msch/Mpz⁺ involves: 129S7/SvEvBrd * C57BL/6	abnormal myelination	J:67581
	normal immune system phenotype	J:67581
Csf1^op/Csf1^op Sh3bp2^tm1Bjro/Sh3bp2^tm1Bjro involves: 129S4/SvJae * BALB/cJ * C57BL/6J	abnormal lymph node cell ratio	J:117880
	increased circulating tumor necrosis factor level	J:117880
	liver inflammation	J:117880
	normal skeleton phenotype	J:117880
Csf1^{tm1.1(CSF1)Flv}/Csf1^{tm1.1(CSF1)Flv} Csf2/Il3^{tm1.1(CSF2,IL3)Flv}/Csf2/Il3^{tm1.1(CSF2,IL3)Flv} Il2rg^tm1.1Flv/Il2rg^tm1.1Flv Rag2^tm1.1Flv/Rag2^tm1.1Flv Tg(SIRPA)1Flv/0 Thpo^{tm1.1(TPO)Flv}/Thpo^{tm1.1(TPO)Flv} involves: 129S4/SvJae * BALB/cAnNTac	abnormal response to transplant	J:207289
Csf1^{tm1.1(CSF1)Flv}/Csf1^{tm1.1(CSF1)Flv} Csf2/Il3^{tm1.1(CSF2,IL3)Flv}/Csf2/Il3^{tm1.1(CSF2,IL3)Flv} Il2rg^tm1.1Flv/Il2rg^tm1.1Flv Rag2^tm1.1Flv/Rag2^tm1.1Flv Thpo^{tm1.1(TPO)Flv}/Thpo^{tm1.1(TPO)Flv} involves: 129S4/SvJae * BALB/cAnNTac	abnormal response to transplant	J:207289
Csf1^{tm1.1(CSF1)Flv}/Csf1^{tm1.1(CSF1)Flv} Il2rg^tm1.1Flv/Il2rg^tm1.1Flv Csf2/Il3^{tm1.1(CSF2,IL3)Flv}/Csf2/Il3^{tm1.1(CSF2,IL3)Flv} Rag2^tm1.1Flv/Rag2^tm1.1Flv Tg(SIRPA)1Flv/0 Thpo^{tm1.1(TPO)Flv}/Thpo^{tm1.1(TPO)Flv} involves: 129S4/SvJae * BALB/cAnNTac	abnormal response to transplant	J:207289
Csf1^{tm1.1(CSF1)Flv}/Csf1^{tm1.1(CSF1)Flv} Il2rg^tm1.1Flv/Il2rg^tm1.1Flv Csf2/Il3^{tm1.1(CSF2,IL3)Flv}/Csf2/Il3^{tm1.1(CSF2,IL3)Flv} Rag2^tm1.1Flv/Rag2^tm1.1Flv Thpo^{tm1.1(TPO)Flv}/Thpo^{tm1.1(TPO)Flv} involves: 129S4/SvJae * BALB/cAnNTac	abnormal response to transplant	J:207289
Csf1^{tm1.1(CSF1)Flv}/Csf1^{tm1.1(CSF1)Flv} Il2rg^tm1.1Flv/Il2rg^tm1.1Flv Rag2^tm1.1Flv/Rag2^tm1.1Flv involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * BALB/cAnNTac	abnormal immune system physiology	J:177073
	normal craniofacial phenotype	J:177073
	normal hematopoietic system phenotype	J:177073
	normal immune system phenotype	J:177073
	normal skeleton phenotype	J:177073

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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