Itsn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itsn1
intersectin 1 (SH3 domain protein 1A)
MGI:1338069

30 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itsn1^em1(IMPC)H/Itsn1⁺ C57BL/6NTac-Itsn1^em1(IMPC)H/H	decreased exploration in new environment	J:211773
Itsn1^em1(IMPC)H/Itsn1^em1(IMPC)H C57BL/6NTac-Itsn1^em1(IMPC)H/H	abnormal gait	J:211773
	abnormal skin coloration	J:211773
	decreased prepulse inhibition	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating amylase level	J:211773
	increased circulating iron level	J:211773
	increased circulating serum albumin level	J:211773
	increased circulating total protein level	J:211773
	limb grasping	J:211773
Itsn1^{Gt(pT1ATGBetageo)1Ruiz}/Itsn1^{Gt(pT1ATGBetageo)1Ruiz} 129.129S2-Itsn1^{Gt(pT1ATGBetageo)1Ruiz}	abnormal anterior commissure morphology	J:196062
	abnormal brain white matter morphology	J:196062
	abnormal corpus callosum morphology	J:196062
	abnormal hippocampal fimbria morphology	J:196062
	abnormal hippocampal fornix morphology	J:196062
	abnormal spatial learning	J:196062
	decreased anterior commissure size	J:196062
	decreased body size	J:196062
	decreased body weight	J:196062
	decreased brain size	J:196062
	impaired contextual conditioning behavior	J:196062
	impaired coordination	J:196062
	normal nervous system phenotype	J:196062
	postnatal growth retardation	J:196062
Itsn1^{Gt(pT1ATGBetageo)1Ruiz}/Itsn1^{Gt(pT1ATGBetageo)1Ruiz} involves: 129S2/SvPas * C57BL/6	prenatal lethality, complete penetrance	J:85162
Itsn1^tm1.1Mapr/Itsn1^tm1.1Mapr involves: 129S6/SvEvTac * 129X1/SvJ	abnormal adrenal gland secretion	J:140030
	abnormal cell morphology	J:140030
	abnormal synaptic vesicle recycling	J:140030
	decreased body size	J:140030
	decreased survivor rate	J:140030
	postnatal growth retardation	J:140030
	premature death	J:140030
Itsn1^tm2.1Mapr/Itsn1^tm2.1Mapr involves: 129S6/SvEvTac * 129X1/SvJ	abnormal adrenal gland secretion	J:140030
	abnormal cell morphology	J:140030
	abnormal synaptic vesicle recycling	J:140030
	decreased body size	J:140030
	decreased survivor rate	J:140030
	postnatal growth retardation	J:140030
	premature death	J:140030

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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