Irag1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irag1
inositol 1,4,5-triphosphate receptor associated 1
MGI:1338023

38 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irag1^{em1(IMPC)Ccpcz}/Irag1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Irag1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal cecum morphology	J:211773
	abnormal freezing behavior	J:211773
	abnormal liver morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hemoglobin content	J:211773
	decreased lymphocyte cell number	J:211773
	enhanced contextual conditioning behavior	J:211773
	enhanced cued conditioning behavior	J:211773
	enlarged cecum	J:211773
	enlarged liver	J:211773
	enlarged spleen	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating glucose level	J:211773
	increased circulating phosphate level	J:211773
	increased circulating triglyceride level	J:211773
	increased effector memory T-helper cell number	J:211773
	increased fasting circulating glucose level	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773
	increased spleen weight	J:211773
	small seminal vesicle	J:211773
	thrombocytosis	J:211773
Irag1^tm1Jens/Irag1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	impaired smooth muscle contractility	J:94387
Irag1^tm1Jens/Irag1^tm1Jens involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal intestinal transit time	J:94387
	decreased heart rate	J:94387
	decreased systemic arterial blood pressure	J:94387
	gastric hypertrophy	J:94387
	impaired smooth muscle contractility	J:94387
	premature death	J:94387
	pyloric stenosis	J:94387
Irag1^tm2.1Jens/Irag1^tm2.1Jens involves: 129S1/Sv * 129X1/SvJ	abnormal digestive system morphology	J:175887
	abnormal systemic arterial blood pressure	J:175887
	abnormal vascular smooth muscle physiology	J:175887
	impaired muscle relaxation	J:175887
	premature death	J:175887

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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