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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tpp1
tripeptidyl peptidase I
MGI:1336194
26 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tpp1m1J/Tpp1m1J
STOCK Tpp1m1J/GrsrJ
hunched posture J:201119
myopathy J:201119
neuronal cytoplasmic inclusions J:201119
premature death J:201119
tremors J:201119
Tpp1tm1.1Plob/Tpp1tm1.1Plob
B6.129S1-Tpp1tm1.1Plob
abnormal brain morphology J:136105
abnormal lysosome physiology J:136105
premature death J:136105
Tpp1tm1Dgen/Tpp1tm1Dgen
involves: 129S1/Sv * C57BL/6
abnormal gait J:101679
abnormal locomotor activation J:101679
abnormal motor capabilities/coordination/movement J:101679
ataxia J:101679
dehydration J:101679
hunched posture J:101679
impaired coordination J:101679
increased thermal nociceptive threshold J:101679
premature death J:101679
respiratory distress J:101679
seizures J:101679
tachypnea J:101679
tremors J:101679
weakness J:101679
Tpp1tm1Plob/Tpp1tm1.1Plob
B6.129S1-Tpp1tm1Plob/Tpp1tm1.1Plob
abnormal gait J:136105
abnormal lysosome physiology J:136105
abnormal Purkinje cell morphology J:136105
ataxia J:136105
premature death J:136105
short stride length J:136105
tremors J:136105
Tpp1tm1Plob/Tpp1tm1Plob
B6.129S1-Tpp1tm1Plob
abnormal brain morphology J:136105
abnormal gait J:136105
abnormal lysosome morphology J:136105
abnormal lysosome physiology J:136105
abnormal Purkinje cell morphology J:136105
ataxia J:136105
premature death J:136105
short stride length J:136105
tremors J:136105
Tpp1tm1Plob/Tpp1tm1Plob
involves: 129S1/Sv
premature death J:94884, J:136105
Tpp1tm1Plob/Tpp1tm1Plob
involves: 129S1/Sv * C57BL/6
abnormal gait J:94884
abnormal lysosome physiology J:94884
ataxia J:94884
audiogenic seizures J:94884
decreased vertical activity J:94884
demyelination J:94884
impaired coordination J:94884
neurodegeneration J:94884
premature death J:94884
Purkinje cell degeneration J:94884
tremors J:94884

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory