Prkaa2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
MGI:1336173

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Prkaa1^tm1.1Mfor/\Prkaa1^tm1.1Mfor \Prkaa2^tm1Vio/\Prkaa2^tm1Vio involves: 129S2/SvPas	normal homeostasis/metabolism phenotype	J:174020
\Prkaa1^tm1.1Sjm/\Prkaa1^tm1.1Sjm \Prkaa2^tm1.1Sjm/\Prkaa2^tm1.1Sjm \Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA * SJL	normal cellular phenotype	J:165090
	decreased hematopoietic stem cell number	J:165090
	normal hematopoietic system phenotype	J:165090
	increased mitochondrial fission	J:165090
\Prkaa1^tm1Sbj/\Prkaa1⁺ \Prkaa2^tm1Vio/\Prkaa2^tm1Vio involves: 129S2/SvPas * FVB/N	increased body weight	J:123951
	increased susceptibility to diet-induced obesity	J:123951
\Prkaa1^tm1Sbj/\Prkaa1^tm1Sbj \Prkaa2^tm1.1Vio/\Prkaa2^tm1.1Vio involves: 129S2/SvPas	normal cellular phenotype	J:141132
\Prkaa1^tm1Sbj/\Prkaa1^tm1Sbj \Prkaa2^tm1Vio/\Prkaa2^tm1Vio \Tg(Pomc1-cre)1Gsb/0 involves: 129S2/SvPas * FVB/N	increased body weight	J:123951
\Prkaa2^tm1Vio/\Prkaa2⁺ \Tg(CAG-Tfb1m)AGsha/0 involves: 129S2/SvPas * C57BL/6J * SJL/J	normal hearing/vestibular/ear phenotype	J:228068

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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