Aqp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aqp3
aquaporin 3
MGI:1333777

23 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aqp3^m1Btlr/Aqp3^m1Btlr C57BL/6J-Aqp3^m1Btlr	abnormal gut-associated lymphoid tissue morphology	J:153279
	increased susceptibility to induced colitis	J:153279
	increased susceptibility to induced morbidity/mortality	J:153279
	increased susceptibility to weight loss	J:153279
	intestinal hemorrhage	J:153279
Aqp3^tm1Ask/Aqp3^tm1Ask involves: C57BL/6J	abnormal renal water transport	J:61675
	decreased circulating triglyceride level	J:61675
	decreased urine osmolality	J:61675
	increased blood osmolality	J:61675
	polydipsia	J:61675
	polyuria	J:61675
Aqp3^tm1Ask/Aqp3^tm1Ask involves: C57BL/6J * CD-1	abnormal olfactory epithelium morphology	J:106285
	normal hearing/vestibular/ear phenotype	J:71154
	normal vision/eye phenotype	J:62579
Aqp3^{tm2b(EUCOMM)Wtsi}/Aqp3^{tm2b(EUCOMM)Wtsi} C57BL/6N-Aqp3^{tm2b(EUCOMM)Wtsi}/H	increased blood urea nitrogen level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating calcium level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating serum albumin level	J:211773
	increased circulating total protein level	J:211773
	increased lean body mass	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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