Dclk1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dclk1
doublecortin-like kinase 1
MGI:1330861

12 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Dclk1^{tm1.1(cre/ERT2)Seno}/\Dclk1^{tm1.1(cre/ERT2)Seno} C57BL/6-Dclk1^{tm1.1(cre/ERT2)Seno}	normal digestive/alimentary phenotype	J:193873
\Dclk1^tm1.1Jgg/\Dclk1⁺ involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6	abnormal corpus callosum morphology	J:105300
\Dclk1^tm1.1Jgg/\Dclk1^tm1.1Jgg involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6	abnormal axon guidance	J:105300
	abnormal corpus callosum morphology	J:105300
	absent corpus callosum	J:105300
	absent hippocampal commissure	J:105300
\Dclk1^{tm1a(EUCOMM)Wtsi}/\Dclk1⁺ C57BL/6N-Dclk1^{tm1a(EUCOMM)Wtsi}/Wtsi	increased anti-nuclear antigen antibody level	J:211773
	increased grip strength	J:211773
\Dclk1^{tm1a(EUCOMM)Wtsi}/\Dclk1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Dclk1^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body length	J:211773
	decreased circulating magnesium level	J:211773
	increased anti-nuclear antigen antibody level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased grip strength	J:211773
\Dclk1^tm1Caw/\Dclk1^tm1Caw involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J	abnormal axon morphology	J:105301
	abnormal neuron morphology	J:105301

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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