Sel1l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sel1l
sel-1 suppressor of lin-12-like (C. elegans)
MGI:1329016

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sel1l^{Gt(CA0017)Wtsi}/Sel1l^{Gt(CA0017)Wtsi} involves: 129P2/OlaHsd	abnormal pancreas development	J:158780
	abnormal pancreas morphology	J:158780
	abnormal pancreatic alpha cell differentiation	J:158780
	abnormal pancreatic beta cell differentiation	J:158780
	decreased hepatocyte proliferation	J:158780
	embryonic lethality during organogenesis, incomplete penetrance	J:158780
	increased endoplasmic reticulum stress	J:158780
	lethality throughout fetal growth and development, complete penetrance	J:158780
Sel1l^{tm1c(KOMP)Wtsi}/Sel1l^{tm1c(KOMP)Wtsi} Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 C57BL/6N * CBA * SJL	abnormal cell morphology	J:206568
	abnormal endoplasmic reticulum morphology	J:206568
	abnormal exocrine pancreas morphology	J:206568
	abnormal intestinal lipid absorption	J:206568
	abnormal pancreatic acinar cell physiology	J:206568
	decreased body size	J:206568
	decreased body temperature	J:206568
	exocrine pancreas atrophy	J:206568
	increased cell death	J:206568
	increased food intake	J:206568
	increased pancreas apoptosis	J:206568
	increased susceptibility to xenobiotic induced morbidity/mortality	J:206568
	moribund	J:206568
	postnatal growth retardation	J:206568
	steatorrhea	J:206568
Sel1l^{tm1e(KOMP)Wtsi}/Sel1l⁺ C57BL/6N-Sel1l^{tm1e(KOMP)Wtsi}/Wtsi	vertebral fusion	J:211773
Sel1l^{tm1e(KOMP)Wtsi}/Sel1l^{tm1e(KOMP)Wtsi} C57BL/6N-Sel1l^{tm1e(KOMP)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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