G0s2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

G0s2
G0/G1 switch gene 2
MGI:1316737

41 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
G0s2^{tm1(KOMP)Vlcg}/G0s2^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal fat cell differentiation	J:232077
	abnormal lactation	J:225236
	abnormal liver morphology	J:209000
	abnormal white adipose tissue physiology	J:209000
	absent gastric milk in neonates	J:225236
	decreased body weight	J:209000, J:232077
	decreased brown adipose tissue amount	J:209000
	decreased circulating alanine transaminase level	J:209000
	decreased circulating aspartate transaminase level	J:209000
	decreased circulating insulin level	J:209000
	decreased epididymal fat pad weight	J:232077
	decreased gonadal fat pad weight	J:209000, J:225236
	decreased inguinal fat pad weight	J:209000
	decreased kidney weight	J:209000
	decreased liver triglyceride level	J:209000
	decreased liver weight	J:209000
	decreased locomotor activity	J:225236
	decreased omental fat pad weight	J:209000
	decreased renal fat pad weight	J:209000
	decreased susceptibility to diet-induced hepatic steatosis	J:209000
	decreased susceptibility to induced hypothermia	J:225236
	decreased total body fat amount	J:232077
	decreased white fat cell size	J:232077
	enhanced lipolysis	J:209000, J:225236
	improved glucose tolerance	J:209000
	increased circulating free fatty acids level	J:209000
	increased circulating glycerol level	J:225236
	increased insulin sensitivity	J:209000
	increased oxygen consumption	J:225236
	normal liver/biliary system phenotype	J:232077
	maternal effect	J:225236
	slow postnatal weight gain	J:225236
G0s2^tm1Jgte/G0s2^tm1Jgte involves: 129S7/SvEvBrd	abnormal brown adipose tissue thermogenesis	J:219653
	abnormal white adipose tissue physiology	J:219653
	decreased abdominal adipose tissue amount	J:219653
	decreased body fat mass	J:219653
	decreased body weight	J:219653
	decreased liver triglyceride level	J:219653
	decreased liver weight	J:219653
	decreased respiratory quotient	J:219653
	decreased susceptibility to diet-induced hepatic steatosis	J:219653
	decreased susceptibility to diet-induced obesity	J:219653
	decreased susceptibility to induced hypothermia	J:219653
	decreased total fat pad weight	J:219653
	decreased white adipose tissue mass	J:219653
	decreased white fat cell size	J:219653
	enhanced lipolysis	J:219653
	improved glucose tolerance	J:219653
	increased insulin sensitivity	J:219653
	increased lean body mass	J:219653
	increased oxygen consumption	J:219653
	increased triglyceride lipase activity	J:219653

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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