Fzd9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fzd9
frizzled class receptor 9
MGI:1313278

39 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fzd9^tm1Lex/Fzd9^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal bone structure	J:103485
	decreased body length	J:103485
	decreased body weight	J:103485
	postnatal growth retardation	J:103485
Fzd9^tm1Sjp/Fzd9⁺ involves: C57BL/6J	abnormal dentate gyrus morphology	J:99893
Fzd9^tm1Sjp/Fzd9⁺ involves: C57BL/6J	abnormal forebrain development	J:99893
Fzd9^tm1Sjp/Fzd9^tm1Sjp involves: C57BL/6J	abnormal dentate gyrus morphology	J:99893
	abnormal forebrain development	J:99893
	abnormal spatial learning	J:99893
	increased susceptibility to pharmacologically induced seizures	J:99893
Fzd9^tm1Uta/Fzd9⁺ involves: 129X1/SvJ	abnormal bone ossification	J:169924
	decreased bone mineral density	J:169924
	decreased bone strength	J:169924
	decreased compact bone thickness	J:169924
	decreased osteoblast cell number	J:169924
	decreased trabecular bone volume	J:169924
Fzd9^tm1Uta/Fzd9^tm1Uta involves: 129S6/SvEvTac * 129X1/SvJ	abnormal lymph node medullary cord morphology	J:98133
	abnormal lymph node morphology	J:98133
	abnormal spleen marginal zone morphology	J:98133
	abnormal spleen red pulp morphology	J:98133
	normal behavior/neurological phenotype	J:98133
	decreased B cell number	J:98133
	decreased pre-B cell number	J:98133
	decreased pro-B cell number	J:98133
	enlarged lymph nodes	J:98133
	enlarged spleen	J:98133
	increased eosinophil cell number	J:98133
	increased leukocyte cell number	J:98133
	increased monocyte cell number	J:98133
	increased neutrophil cell number	J:98133
	premature death	J:98133
	thymus atrophy	J:98133
Fzd9^tm1Uta/Fzd9^tm1Uta involves: 129X1/SvJ	abnormal skeleton development	J:169924
	abnormal skeleton physiology	J:169924
	abnormal vertebral body morphology	J:169924
	decreased bone mineral density	J:169924
	decreased bone mineralization	J:169924
	decreased bone ossification	J:169924
	decreased bone strength	J:169924
	decreased bone trabecula number	J:169924
	decreased bone volume	J:169924
	decreased compact bone thickness	J:169924
	decreased osteoblast cell number	J:169924
	decreased osteoblast proliferation	J:169924
	impaired osteoblast differentiation	J:169924

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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