Mpzl2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mpzl2
myelin protein zero-like 2
MGI:1289160

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mpzl2^em1Shuy/Mpzl2^em1Shuy involves: FVB/NJ	cochlear outer hair cell degeneration	J:370428
	degeneration of organ of Corti supporting cells	J:370428
	Deiters cell degeneration	J:370428
	impaired hearing	J:370428
	increased or absent distortion product otoacoustic emission threshold	J:370428
	increased or absent threshold for auditory brainstem response	J:370428
	normal nervous system phenotype	J:370428
Mpzl2^{tm1b(EUCOMM)Hmgu}/Mpzl2⁺ C57BL/6N-Mpzl2^{tm1b(EUCOMM)Hmgu}/Bay	increased red blood cell distribution width	J:211773
	long tibia	J:211773
Mpzl2^{tm1b(EUCOMM)Hmgu}/Mpzl2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Mpzl2^{tm1b(EUCOMM)Hmgu}/Bay	abnormal coat/hair pigmentation	J:211773
	abnormal ear morphology	J:211773
	abnormal gait	J:211773
	increased total body fat amount	J:211773
Mpzl2^tm1Lex/Mpzl2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased B cell number	J:171883
	increased CD8-positive, alpha-beta T cell number	J:171883

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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