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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tyrobp
TYRO protein tyrosine kinase binding protein
MGI:1277211
29 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fcer1gtm1Rav/Fcer1gtm1Rav
Tyrobptm1.1Viv/Tyrobptm1.1Viv
involves: 129P2/OlaHsd * C57BL/6 		abnormal decidua basalis morphology J:100668
abnormal maternal decidual layer morphology J:100668
abnormal uterine spiral artery morphology J:100668
abnormal uterine spiral artery remodeling J:100668
decreased interferon-gamma secretion J:100668
decreased uterine NK cell number J:100668
reduced fertility J:100668
small placenta J:100668
Fcer1gtm1Rav/Fcer1gtm1Rav
Tyrobptm1Lll/Tyrobptm1Lll
involves: 129P2/OlaHsd 		abnormal osteoclast physiology J:147155
Fcer1gtm1Rav/Fcer1gtm1Rav
Tyrobptm1Lll/Tyrobptm1Lll
involves: 129P2/OlaHsd * C57BL/6 		abnormal bone marrow cavity morphology J:89583
abnormal bone structure J:89583
abnormal osteoclast differentiation J:89583
abnormal trabecular bone morphology J:89583
decreased body size J:89583
decreased bone resorption J:89583
increased bone mass J:89583
increased diameter of femur J:89583
osteopetrosis J:89583
round face J:89583
short femur J:89583
normal skeleton phenotype J:89583
Hcsttm1.1Cln/Hcsttm1.1Cln
Tyrobptm1Lll/Tyrobptm1Lll
B6.Cg-Hcsttm1.1Cln Tyrobptm1Lll 		abnormal NK T cell physiology J:147867
abnormal response to infection J:147867
Oscartm1Ywc/Oscartm1Ywc
Tyrobptm1Ttk/Tyrobptm1Ttk
involves: 129P2/OlaHsd * C57BL/6 		abnormal osteoclast differentiation J:178250
abnormal osteoclast morphology J:178250
abnormal osteoclast physiology J:178250
abnormal trabecular bone morphology J:178250
decreased osteoclast cell number J:178250
increased bone trabecula number J:178250
increased trabecular bone volume J:178250
normal skeleton phenotype J:178250
Rag1tm1Mom/Rag1tm1Mom
Tyrobptm1.1Viv/Tyrobptm1.1Viv
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/10 		abnormal bone remodeling J:129304
abnormal osteoclast physiology J:129304
increased bone mass J:129304
increased bone trabecula number J:129304
increased trabecular bone connectivity density J:129304
osteopetrosis J:129304
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory