About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Robo1
roundabout guidance receptor 1
MGI:1274781
54 phenotypes from 6 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Robo1b2b872Clo/Robo1b2b872Clo
C57BL/6J-Robo1b2b872Clo
abnormal craniofacial morphology J:244438
abnormal heart morphology J:244438
abnormal kidney morphology J:175213
abnormal sex gland morphology J:175213
atrioventricular septal defect J:244438
cleft palate J:175213, J:244438
double outlet right ventricle J:175213, J:244438
heart left ventricle hypertrophy J:175213
heart right ventricle hypertrophy J:175213
hydronephrosis J:175213
hydroureter J:175213
micrognathia J:175213, J:244438
muscular ventricular septal defect J:244438
ostium secundum atrial septal defect J:244438
perimembraneous ventricular septal defect J:244438
polycystic kidney J:175213
short snout J:244438
ventricular septal defect J:175213
Robo1em1(IMPC)Mbp/Robo1+
C57BL/6N-Robo1em1(IMPC)Mbp/MbpMmucd
abnormal behavior J:211773
decreased anxiety-related response J:211773
decreased locomotor activity J:211773
decreased thigmotaxis J:211773
no spontaneous movement J:211773
Robo1em1(IMPC)Mbp/Robo1em1(IMPC)Mbp
C57BL/6N-Robo1em1(IMPC)Mbp/MbpMmucd
no spontaneous movement J:211773
preweaning lethality, complete penetrance J:211773
preweaning lethality, incomplete penetrance J:211773
Robo1tm1.1Ljr/Robo1tm1.1Ljr
B6.129-Robo1tm1.1Ljr
abnormal axon extension J:109478
abnormal axon guidance J:109478
abnormal brain commissure morphology J:109478
abnormal corpus callosum morphology J:109478
abnormal hippocampal commissure morphology J:109478
abnormal neuronal migration J:109478
decreased corpus callosum size J:109478
decreased hippocampal commissure size J:109478
perinatal lethality, complete penetrance J:109478
Robo1tm1Matl/Robo1tm1Matl
involves: 129X1/SvJ
abnormal mammary gland duct morphology J:106011, J:141875
abnormal olfactory tract morphology J:119469
increased mammary gland epithelial cell proliferation J:141875
Robo1tm1Matl/Robo1tm1Matl
involves: CD-1
abnormal axon guidance J:89780
abnormal spinal cord lateral column morphology J:89780
Robo1tm1Phr/Robo1+
involves: 129P2/OlaHsd * C57BL/6
increased carcinoma incidence J:93666
increased lung adenocarcinoma incidence J:93666
increased lymphoma incidence J:93666
Robo1tm1Phr/Robo1tm1Phr
involves: 129P2/OlaHsd * C57BL/6
abnormal bronchiole morphology J:73485
abnormal bronchus morphology J:73485
abnormal lung development J:73485
abnormal lung morphology J:73485
abnormal pulmonary alveolus morphology J:73485
abnormal pulmonary interalveolar septum morphology J:73485
aphagia J:73485
bronchial epithelial hyperplasia J:73485
neonatal lethality, incomplete penetrance J:73485
respiratory failure J:73485
thick pulmonary interalveolar septum J:73485
Robo1tm1Wian/Robo1tm1Wian
involves: 129S/SvEv
perimembraneous ventricular septal defect J:244438
Robo1tm1Wian/Robo1tm1Wian
involves: 129S/SvEv * C57BL/6
abnormal embryonic/fetal subventricular zone morphology J:130430
abnormal neurite morphology J:130430

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory