Il12rb2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il12rb2
interleukin 12 receptor, beta 2
MGI:1270861

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il12rb2^tm1Jm/Il12rb2^tm1Jm B6;129S1-Il12rb2^tm1Jm/J	abnormal B cell activation	J:106805
	abnormal T cell activation	J:106805
	abnormal tumor morphology	J:120061
	abnormal tumor vascularization	J:120061
	decreased tumor growth/size	J:120061
	glomerulonephritis	J:106805
	increased anti-nuclear antigen antibody level	J:106805
	increased circulating interleukin-12 level	J:120061
	increased interleukin-6 secretion	J:106805
	increased lung carcinoma incidence	J:106805
	increased plasmacytoma incidence	J:106805
	liver inflammation	J:106805
	lymphoid hyperplasia	J:106805
	parotid gland inflammation	J:106805
	salivary gland inflammation	J:106805
	submandibular gland inflammation	J:106805
Il12rb2^tm1Jm/Il12rb2^tm1Jm either: (involves: 129S1/Sv * BALB/cByJ) or (involves: 129S1/Sv * C57BL/6J)	abnormal lymphocyte physiology	J:65891
	abnormal NK cell physiology	J:65891

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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