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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ddb1
damage specific DNA binding protein 1
MGI:1202384
36 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ddb1em1(IMPC)Ccpcz/Ddb1+
C57BL/6N-Ddb1em1(IMPC)Ccpcz/Ccpcz
abnormal auditory brainstem response J:211773
abnormal skin morphology J:211773
abnormal thymus morphology J:211773
abnormal urinary bladder morphology J:211773
enlarged thymus J:211773
enlarged urinary bladder J:211773
hyperactivity J:211773
Ddb1em1(IMPC)Ccpcz/Ddb1em1(IMPC)Ccpcz
C57BL/6N-Ddb1em1(IMPC)Ccpcz/Ccpcz
embryonic lethality prior to organogenesis J:211773
Ddb1tm1.1Spg/Ddb1tm1.1Spg
involves: 129P2/OlaHsd
embryonic lethality during organogenesis, complete penetrance J:117820
Ddb1tm1Spg/Ddb1tm1Spg
Plekha5Tg(AMH-cre)1Flor/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
abnormal seminiferous tubule morphology J:291677
abnormal testis cord formation J:291677
decreased Sertoli cell number J:291677
ectopic Sertoli cells J:291677
enlarged seminiferous tubules J:291677
oligozoospermia J:291677
small testis J:291677
Ddb1tm1Spg/Ddb1tm1Spg
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
abnormal blood vessel morphology J:117820
abnormal cerebellum external granule cell layer morphology J:117820
abnormal cerebral aqueduct morphology J:117820
abnormal cerebral cortex morphology J:117820
abnormal fourth ventricle morphology J:117820
abnormal lateral ventricle morphology J:117820
abnormal lens morphology J:117820
abnormal nervous system physiology J:117820
abnormal neuron apoptosis J:117820
abnormal olfactory bulb morphology J:117820
cataract J:117820
cerebellum hemorrhage J:117820
decreased brain size J:117820
enlarged lateral ventricles J:117820
increased lens epithelium apoptosis J:117820
intracerebral hemorrhage J:117820
intracranial hemorrhage J:117820
neonatal lethality, complete penetrance J:117820
small cerebellum J:117820
thin cerebral cortex J:117820

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory