Nmt2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nmt2
N-myristoyltransferase 2
MGI:1202298

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nmt1^tm1.1Poru/Nmt1^tm1.1Poru Nmt2^tm1.1Poru/Nmt2^tm1.1Poru Tg(Lck-cre)1Cwi/0 involves: C57BL/6 * DBA/2 * SJL	abnormal CD4-positive, alpha beta T cell morphology	J:226234
	abnormal CD8-positive, alpha beta T cell morphology	J:226234
	decreased circulating interferon-gamma level	J:226234
	decreased circulating interleukin-2 level	J:226234
	decreased circulating tumor necrosis factor level	J:226234
	decreased DN4 thymocyte number	J:226234
	decreased double-positive T cell number	J:226234
	decreased interferon-gamma secretion	J:226234
	decreased interleukin-2 secretion	J:226234
	decreased single-positive T cell number	J:226234
	decreased splenocyte proliferation	J:226234
	decreased susceptibility to endotoxin shock	J:226234
	decreased T cell number	J:226234
	decreased T cell proliferation	J:226234
	normal immune system phenotype	J:226234
	increased double-negative T cell number	J:226234
	increased gamma-delta T cell number	J:226234
	increased T cell apoptosis	J:226234
	small thymus medulla	J:226234

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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