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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Socs2
suppressor of cytokine signaling 2
MGI:1201787
51 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Socs2em1(IMPC)H/Socs2em1(IMPC)H
C57BL/6NTac-Socs2em1(IMPC)H/H
decreased grip strength J:211773
increased circulating creatinine level J:211773
increased spleen weight J:211773
Socs2m1Btlr/Socs2m1Btlr
C57BL/6J-Socs2m1Btlr
increased body weight J:221476
Socs2tm1Vem/Socs2tm1Vem
involves: 129P2/OlaHsd * C57BL/6J
abnormal bone trabecula morphology J:225936
abnormal long bone epiphyseal plate proliferative zone J:225936
abnormal tibia morphology J:225936
decreased bone trabecular spacing J:225936
increased body weight J:225936
increased bone trabecula number J:225936
increased compact bone area J:225936
increased diameter of tibia J:225936
increased long bone epiphyseal plate size J:225936
increased trabecular bone thickness J:225936
increased trabecular bone volume J:225936
increased width of hypertrophic chondrocyte zone J:225936
long tibia J:225936
normal skeleton phenotype J:225936
Socs2tm1Wehi/Socs2+
C57BL/6-Socs2tm1Wehi
increased body weight J:63006
Socs2tm1Wehi/Socs2tm1Wehi
C57BL/6-Socs2tm1Wehi
abnormal hepatobiliary system morphology J:63006
abnormal insulin-like growth factor I level J:63006
abnormal lung morphology J:63006
abnormal pancreatic duct morphology J:63006
abnormal salivary gland duct morphology J:63006
abnormal urine homeostasis J:63006
normal adipose tissue phenotype J:63006
increased body length J:63006
increased body weight J:63006
increased growth rate J:63006
increased length of long bones J:63006
long femur J:63006
long humerus J:63006
long radius J:63006
long tibia J:63006
thick dermal layer J:63006
Socs2tm1Wehi/Socs2tm1Wehi
involves: C57BL/6 * C57BL/6J
abnormal circulating cytokine level J:186227
abnormal circulating hormone level J:186227
abnormal glucose homeostasis J:186227
abnormal macrophage physiology J:186227
decreased circulating growth hormone level J:186227
decreased circulating insulin-like growth factor I level J:186227
decreased liver triglyceride level J:186227
decreased susceptibility to diet-induced hepatic steatosis J:186227
impaired glucose tolerance J:186227
increased circulating glucose level J:186227
increased circulating insulin level J:186227
increased circulating interferon-gamma level J:186227
increased circulating interleukin-1 beta level J:186227
increased interferon-gamma secretion J:186227
increased interleukin-1 beta secretion J:186227
increased renal fat pad weight J:186227
increased skeletal muscle triglyceride level J:186227
increased tumor necrosis factor secretion J:186227
insulin resistance J:186227
liver inflammation J:186227

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory