Birc3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Birc3
baculoviral IAP repeat-containing 3
MGI:1197007

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr involves: BALB/cJ * C57BL/6 * SJL	abnormal heart atrium morphology	J:182515
	congestive heart failure	J:182515
	decreased cardiac muscle contractility	J:182515
	embryonic lethality during organogenesis, complete penetrance	J:182515
	enlarged pericardium	J:182515
	hemopericardium	J:182515
	hemorrhage	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Ripk1^tm1Led/Ripk1⁺ involves: 129S6/SvEvTac * BALB/cJ * C57BL/6 * SJL	lethality throughout fetal growth and development, complete penetrance	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Ripk1^tm1Led/Ripk1^tm1Led involves: 129S6/SvEvTac * BALB/cJ * C57BL/6 * SJL	embryonic lethality during organogenesis, complete penetrance	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Ripk3^tm1Vmd/Ripk3⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 * SJL	embryonic lethality during organogenesis, complete penetrance	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Ripk3^tm1Vmd/Ripk3^tm1Vmd involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 * SJL	lethality throughout fetal growth and development, complete penetrance	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Tnfrsf1a^tm1Imx/Tnfrsf1a^tm1Imx involves: BALB/cJ * C57BL/6 * SJL	postnatal lethality, complete penetrance	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Tnfrsf1b^tm1Imx/Tnfrsf1b^tm1Imx involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6 * SJL	embryonic lethality during organogenesis, complete penetrance	J:182515
Birc2^tm1.1Rbr/Birc2^tm1.1Rbr Birc3^tm1Rbr/Birc3^tm1Rbr involves: BALB/cJ * C57BL/6	no abnormal phenotype detected	J:182515
Birc2^tm1Rbr/Birc2^tm1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr involves: C57BL/6 * NZB	normal immune system phenotype	J:172843
Birc2^tm1Rbr/Birc2^tm1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr involves: C57BL/6 * SJL	no abnormal phenotype detected	J:182515
Birc2^tm1Rbr/Birc2^tm1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * C57BL/6 * NZB	decreased B cell apoptosis	J:172843
	decreased germinal center B cell number	J:172843
	decreased spleen germinal center size	J:172843
	enlarged lymph nodes	J:172843
	enlarged spleen	J:172843
	increased B cell number	J:172843
	increased follicular B cell number	J:172843
	increased marginal zone B cell number	J:172843
Birc2^tm1Rbr/Birc2^tm1Rbr Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Cd19^tm1(cre)Cgn/Cd19⁺ Tnfrsf13c^tm1Mass/Tnfrsf13c^tm1Mass involves: 129P2/OlaHsd * C57BL/6 * NZB	normal immune system phenotype	J:172843
Birc2^tm1Rbr/Birc2^tm1Rbr Birc3^tm1Rbr/Birc3^tm1Rbr involves: C57BL/6	no abnormal phenotype detected	J:182515
Birc2^tm1Rbr/Birc2^tm1Rbr Birc3^tm1Rbr/Birc3^tm1Rbr Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * C57BL/6 * NZB	normal immune system phenotype	J:172843
Birc3^tm1.1Rbr/Birc3^tm1.1Rbr Xiap^tm1Vdr/Xiap^tm1Vdr involves: 129S1/Sv * C57BL/6 * SJL	no abnormal phenotype detected	J:182515

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