Dsc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dsc3
desmocollin 3
MGI:1194993

19 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Dsc3^{tm1b(EUCOMM)Wtsi}/\Dsc3⁺ C57BL/6N-Dsc3^{tm1b(EUCOMM)Wtsi}/H	abnormal behavior	J:211773
	absent optic nerve	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
\Dsc3^{tm1b(EUCOMM)Wtsi}/\Dsc3^{tm1b(EUCOMM)Wtsi} C57BL/6N-Dsc3^{tm1b(EUCOMM)Wtsi}/H	preweaning lethality, complete penetrance	J:211773
\Dsc3^tm1Pko/\Dsc3⁺ involves: 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:105239
\Dsc3^tm1Pko/\Dsc3^tm1Pko involves: 129S6/SvEvTac * C57BL/6	embryonic lethality before implantation, complete penetrance	J:105239
\Dsc3^tm2Pko/\Dsc3^tm2Pko involves: 129S6/SvEvTac	no abnormal phenotype detected	J:140129
\Dsc3^tm2Pko/\Dsc3^tm2Pko \Tg(KRT14-cre)1Amc/0 involves: 129S6/SvEvTac * C57BL/6 * CBA	absent epidermis	J:140129
	acantholysis	J:140129
	blistering	J:140129
	decreased keratinocyte adhesion	J:140129
	decreased survivor rate	J:140129
	epidermal cyst	J:140129
	epidermal hyperplasia	J:140129
	normal integument phenotype	J:140129
	neonatal lethality, incomplete penetrance	J:140129
	skin lesions	J:140129
	sparse hair	J:140129

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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