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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dsc3
desmocollin 3
MGI:1194993
19 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
\Dsc3tm1b(EUCOMM)Wtsi/\Dsc3+
C57BL/6N-Dsc3tm1b(EUCOMM)Wtsi/H
abnormal behavior J:211773
absent optic nerve J:211773
decreased fasting circulating glucose level J:211773
decreased thigmotaxis J:211773
hyperactivity J:211773
\Dsc3tm1b(EUCOMM)Wtsi/\Dsc3tm1b(EUCOMM)Wtsi
C57BL/6N-Dsc3tm1b(EUCOMM)Wtsi/H
preweaning lethality, complete penetrance J:211773
\Dsc3tm1Pko/\Dsc3+
involves: 129S6/SvEvTac * C57BL/6
no abnormal phenotype detected J:105239
\Dsc3tm1Pko/\Dsc3tm1Pko
involves: 129S6/SvEvTac * C57BL/6
embryonic lethality before implantation, complete penetrance J:105239
\Dsc3tm2Pko/\Dsc3tm2Pko
involves: 129S6/SvEvTac
no abnormal phenotype detected J:140129
\Dsc3tm2Pko/\Dsc3tm2Pko
\Tg(KRT14-cre)1Amc/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
absent epidermis J:140129
acantholysis J:140129
blistering J:140129
decreased keratinocyte adhesion J:140129
decreased survivor rate J:140129
epidermal cyst J:140129
epidermal hyperplasia J:140129
normal integument phenotype J:140129
neonatal lethality, incomplete penetrance J:140129
skin lesions J:140129
sparse hair J:140129

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory