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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
MGI:1101059
26 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tnfrsf9em1Ygch/Tnfrsf9em1Ygch
NOD/ShiLtDvs-Tnfrsf9em1Ygch 		abnormal glucose homeostasis J:208927
abnormal T cell physiology J:208927
normal immune system phenotype J:208927
insulitis J:208927
Tnfrsf9em2Ygch/Tnfrsf9em2Ygch
NOD/ShiLtDvs-Tnfrsf9em2Ygch 		abnormal glucose homeostasis J:208927
abnormal T cell physiology J:208927
normal immune system phenotype J:208927
insulitis J:208927
Tnfrsf9m1Btlr/Tnfrsf9m1Btlr
C57BL/6J-Tnfrsf9m1Btlr 		decreased CD8-positive, alpha-beta T cell number J:265260
decreased CD8-positive, naive alpha-beta T cell number J:265260
decreased single-positive T cell number J:265260
increased B cell number J:265260
increased effector memory CD4-positive, alpha-beta T cell number J:265260
increased effector memory CD8-positive, alpha-beta T cell number J:265260
Tnfrsf9tm1b(EUCOMM)Wtsi/Tnfrsf9tm1b(EUCOMM)Wtsi
C57BL/6N-Tnfrsf9tm1b(EUCOMM)Wtsi/Ics 		preweaning lethality, incomplete penetrance J:211773
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
B6.Cg-Tnfrsf9tm1Byk 		abnormal common myeloid progenitor cell morphology J:83996
abnormal cytotoxic T cell physiology J:83996
decreased IgG2a level J:83996
decreased IgG3 level J:83996
decreased interferon-gamma secretion J:83996
decreased interleukin-2 secretion J:83996
decreased interleukin-4 secretion J:83996
increased T cell proliferation J:83996
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
C.Cg-Tnfrsf9tm1Byk 		abnormal common myeloid progenitor cell morphology J:83996
abnormal cytotoxic T cell physiology J:83722
abnormal immunoglobulin level J:83996
decreased IgG2a level J:83996
decreased IgG3 level J:83996
decreased interferon-gamma secretion J:83996
decreased interleukin-2 secretion J:83996
decreased interleukin-4 secretion J:83996
decreased interleukin-12 secretion J:83722
increased IgA level J:83722
increased IgG2a level J:83722
increased IgG2b level J:83722
increased splenocyte proliferation J:83722
increased T cell proliferation J:83996
Tnfrsf9tm1Lpc/Tnfrsf9tm1Lpc
B6.129-Tnfrsf9tm1Lpc 		abnormal memory T cell physiology J:145439
normal immune system phenotype J:145439
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory