89 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Med1tm1.1Mpk/Med1tm1.1Mpk involves: 129P2/OlaHsd * C57BL/6J	abnormal eye development	J:86857
	abnormal heart morphology	J:86857
	abnormal limb morphology	J:86857
	absent megakaryocytes	J:86857
	embryonic lethality during organogenesis, complete penetrance	J:86857
	impaired placental function	J:86857
	increased nucleated erythrocyte cell number	J:86857
	thin ventricular wall	J:86857
	trabecula carnea hypoplasia	J:86857
	ventricular hypoplasia	J:86857
Med1tm1Jkr/Med1tm1Jkr involves: 129P2/OlaHsd * C57BL/6	abnormal cardiovascular development	J:74328
	abnormal cardiovascular system morphology	J:74328
	abnormal cardiovascular system physiology	J:62272, J:74328
	abnormal definitive hematopoiesis	J:74328
	abnormal extraembryonic tissue morphology	J:62272
	abnormal lens development	J:74328
	abnormal lens epithelium morphology	J:74328
	abnormal placenta labyrinth morphology	J:62272
	abnormal placenta vasculature	J:62272, J:74328
	abnormal placental labyrinth vasculature morphology	J:62272
	abnormal retina pigmentation	J:74328
	abnormal spongiotrophoblast layer morphology	J:62272
	abnormal trophoblast giant cell morphology	J:62272
	abnormal vascular endothelial cell development	J:74328
	absent megakaryocytes	J:74328
	decreased embryo size	J:62272
	dilated liver sinusoidal space	J:74328
	embryonic growth retardation	J:62272
	embryonic lethality during organogenesis, complete penetrance	J:62272
	increased angiogenesis	J:74328
	increased vascular permeability	J:74328
	myocardial trabeculae hypoplasia	J:74328
	myocardium hypoplasia	J:74328
	pericardial effusion	J:74328
	thin myocardium	J:62272
	thin ventricular wall	J:74328
	trabecula carnea hypoplasia	J:74328
	ventricular hypoplasia	J:74328
Med1tm1Mpk/Med1tm1Mpk involves: 129P2/OlaHsd * C57BL/6J	abnormal eye development	J:86857
	abnormal heart morphology	J:86857
	abnormal limb morphology	J:86857
	embryonic growth retardation	J:86857
	embryonic lethality during organogenesis, complete penetrance	J:86857
	increased nucleated erythrocyte cell number	J:86857
	thin ventricular wall	J:86857
	trabecula carnea hypoplasia	J:86857
Med1tm1Rgr/Med1+ either: 129X1/SvJ or (involves: 129X1/SvJ * C57BL/6J)	abnormal metabolism	J:61840
	decreased activity of thyroid gland	J:61840
	decreased body height	J:61840
	decreased body size	J:61840
	decreased circulating thyroxine level	J:61840
	decreased circulating triiodothyronine level	J:61840
	decreased thyroid-stimulating hormone level	J:61840
	postnatal growth retardation	J:61840
Med1tm1Rgr/Med1tm1Rgr either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * 129X1/SvJ)	abnormal blood vessel morphology	J:61840
	abnormal brain morphology	J:61840
	abnormal bronchus morphology	J:61840
	abnormal cardiovascular system morphology	J:61840
	abnormal cardiovascular system physiology	J:61840
	abnormal cell cycle	J:61840
	abnormal embryonic neuroepithelium morphology	J:61840
	abnormal forebrain development	J:61840
	abnormal liver development	J:61840
	abnormal myocardial trabeculae morphology	J:61840
	abnormal nervous system morphology	J:61840
	abnormal neuron apoptosis	J:61840
	abnormal telencephalon development	J:61840
	abnormal vena cava morphology	J:61840
	decreased embryo size	J:61840
	decreased fibroblast proliferation	J:61840
	embryonic lethality between somite formation and embryo turning, incomplete penetrance	J:61840
	embryonic lethality, complete penetrance	J:61840
	enlarged heart	J:61840
	heart hypoplasia	J:61840
	microcephaly	J:61840
	postnatal growth retardation	J:61840
	thin myocardium compact layer	J:61840
	thin ventricular wall	J:61840
	trabecula carnea hypoplasia	J:61840
Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ involves: 129P2/OlaHsd * FVB/N	abnormal heart echocardiography feature	J:243730
	abnormal heart morphology	J:243730
	cardiac interstitial fibrosis	J:243730
	congestive heart failure	J:243730
	decreased cardiac muscle contractility	J:243730
	dilated cardiomyopathy	J:243730
	dilated heart ventricle	J:243730
	enlarged heart	J:243730
	increased cardiomyocyte apoptosis	J:243730
	premature death	J:243730
	thin ventricular wall	J:243730
Med1tm2Jkr/Med1tm2Jkr Tg(Alb1-cre)1Dlr/0 involves: 129P2/OlaHsd * C57BL/6	abnormal hepatocyte morphology	J:94123
Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 involves: 129P2/OlaHsd * FVB/N	abnormal heart echocardiography feature	J:243730
	abnormal myocardial fiber morphology	J:243730
	abnormal Z line morphology	J:243730
	cardiac edema	J:243730
	cardiac interstitial fibrosis	J:243730
	congestive heart failure	J:243730
	decreased cardiac muscle contractility	J:243730
	decreased myocardial fiber mitochondrial DNA content	J:243730
	dilated cardiomyopathy	J:243730
	dilated heart atrium	J:243730
	dilated heart ventricle	J:243730
	enlarged heart	J:243730
	increased cardiomyocyte apoptosis	J:243730
	premature death	J:243730
	pulmonary edema	J:243730
	thin ventricular wall	J:243730
Med1tm2Rgr/Med1tm2Rgr B6.129P2-Med1tm2Rgr	abnormal branching of the mammary ductal tree	J:159303
	abnormal mammary gland development	J:159303
	abnormal mammary gland epithelium morphology	J:159303
	decreased mammary gland epithelial cell proliferation	J:159303
Med1tm3b(EUCOMM)Wtsi/Med1+ C57BL/6N-Med1tm3b(EUCOMM)Wtsi/Tcp	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	enlarged heart	J:211773
	enlarged uterus	J:211773
	hydrometra	J:211773
	small superior vagus ganglion	J:211773
Med1tm3b(EUCOMM)Wtsi/Med1tm3b(EUCOMM)Wtsi C57BL/6N-Med1tm3b(EUCOMM)Wtsi/Tcp	abnormal embryo size	J:211773
	abnormal eye morphology	J:211773
	abnormal placenta size	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	pale yolk sac	J:211773
	pallor	J:211773
	preweaning lethality, complete penetrance	J:211773