125 phenotypes from 10 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(APCS-Tnfsf11*)#aKhs/0 C57BL/6J-Tg(APCS-Tnfsf11*)#aKhs	abnormal osteoclast morphology	J:264357
	decreased bone mineral density of femur	J:264357
	decreased bone stiffness	J:264357
	decreased bone strength	J:264357
	decreased trabecular bone mass	J:264357
	enlarged thymus medulla	J:264357
	fragile skeleton	J:264357
	increased bone resorption	J:264357
	increased circulating alkaline phosphatase level	J:264357
	increased osteoclast cell number	J:264357
	osteoporosis	J:264357
	perinatal lethality, incomplete penetrance	J:264357
	postnatal lethality, incomplete penetrance	J:264357
	skin edema	J:264357
Tg(APCS-Tnfsf11*)#bKhs/0 involves: C3H/He * C57BL/6N	decreased trabecular bone mass	J:264357
	osteoporosis	J:264357
Tg(CAG-Tnfsf11*)#Khs/0 either: (involves: C57BL/6N) or (involves: C3H/He * C57BL/6J)	decreased bone mineralization	J:264357
	distended abdomen	J:264357
	perinatal lethality, complete penetrance	J:264357
Tnfsf11gum/Tnfsf11gum STOCK Tnfsf11gum/GrsrJ	abnormal areal bone mineral density	J:223062
	abnormal cranial suture morphology	J:223062
	abnormal craniofacial bone morphology	J:223062
	abnormal hyoid bone body morphology	J:223062
	abnormal long bone internal diameter	J:223062
	abnormal maternal nurturing	J:223062
	abnormal tail length	J:223062
	abnormal zygomatic bone morphology	J:223062
	decreased body size	J:223062
	decreased body weight	J:223062
	decreased internal diameter of femur	J:223062
	decreased lean body mass	J:223062
	dystrophic muscle	J:223062
	failure of tooth eruption	J:223062
	increased areal bone mineral density	J:223062
	increased bone mineral content	J:223062
	mandible hypoplasia	J:223062
	osteopetrosis	J:223062
	reduced fertility	J:223062
	small cranium	J:223062
	supernumerary teeth	J:223062
Tnfsf11tles/Tnfsf11tles involves: 129S6/SvEvTac * C57BL/6J	abnormal osteoblast physiology	J:179743
	abnormal trabecular bone morphology	J:179743
	absent lymph nodes	J:179743
	decreased osteoclast cell number	J:179743
	enlarged spleen	J:179743
	failure of tooth eruption	J:179743
	increased bone trabecula number	J:179743
	increased bone volume	J:179743
	osteopetrosis	J:179743
	postnatal growth retardation	J:179743
	premature death	J:179743
	normal skeleton phenotype	J:179743
	thymus hypoplasia	J:179743
Tnfsf11tles/Tnfsf11tm1Pngr involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	abnormal trabecular bone morphology	J:179743
	decreased osteoclast cell number	J:179743
	failure of tooth eruption	J:179743
	increased bone mass	J:179743
	increased bone trabecula number	J:179743
	increased bone volume	J:179743
	osteopetrosis	J:179743
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob Tg(BGLAP-cre)1Clem/0 involves: 129S * 129X1/SvJ * C57BL/6 * FVB/NJ	abnormal cartilage morphology	J:177558
	failure of tooth eruption	J:177558
	increased bone mineral density	J:177558
	increased long bone epiphyseal plate size	J:177558
	increased trabecular bone volume	J:177558
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob Tg(Col10a1-cre)1427Vdm/0 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6	increased bone mineral density	J:177558
	increased trabecular bone volume	J:177558
	osteopetrosis	J:177558
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob Tg(Dmp1-cre)1Jqfe/0 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB	abnormal bone structure	J:177558
	abnormal osteoclast cell number	J:177558
	decreased compact bone thickness	J:177558
	decreased osteoclast cell number	J:177558
	increased bone mineral density of femur	J:177558
	increased bone mineral density of vertebrae	J:177558
	increased bone trabecular spacing	J:177558
	increased trabecular bone volume	J:177558
	normal skeleton phenotype	J:177558
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob Tg(Prrx1-cre)1Cjt/0 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6	abnormal cartilage morphology	J:177558
	decreased osteoclast cell number	J:177558
	increased bone mineral density	J:177558
	increased long bone epiphyseal plate size	J:177558
	increased trabecular bone volume	J:177558
	osteopetrosis	J:177558
	normal skeleton phenotype	J:177558
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S * 129X1/SvJ * C57BL/6 * CD-1	abnormal cartilage morphology	J:177558
	failure of tooth eruption	J:177558
	increased bone mineral density	J:177558
	increased long bone epiphyseal plate size	J:177558
	increased trabecular bone volume	J:177558
	normal skeleton phenotype	J:177558
Tnfsf11tm1.1Htaka/Tnfsf11tm1.1Htaka B6.Cg-Tnfsf11tm1.1Htaka	normal skeleton phenotype	J:177557
Tnfsf11tm1.1Htaka/Tnfsf11tm1.2Htaka Tg(Dmp1-cre)1Jqfe/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * FVB/N	abnormal bone ossification	J:177557
	abnormal cartilage morphology	J:177557
	decreased bone resorption	J:177557
	decreased osteoclast cell number	J:177557
	normal growth/size/body region phenotype	J:177557
	increased bone mass	J:177557
	increased bone volume	J:177557
	increased trabecular bone volume	J:177557
	osteopetrosis	J:177557
	normal skeleton phenotype	J:177557
Tnfsf11tm1.1Htaka/Tnfsf11tm1.2Htaka Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J	normal skeleton phenotype	J:177557
Tnfsf11tm1.2Htaka/Tnfsf11+ B6.Cg-Tnfsf11tm1.2Htaka	abnormal trabecular bone morphology	J:177557
	decreased osteoclast cell number	J:177557
	increased bone volume	J:177557
Tnfsf11tm1.2Htaka/Tnfsf11tm1.2Htaka B6.Cg-Tnfsf11tm1.2Htaka	abnormal cartilage morphology	J:177557
	abnormal long bone metaphysis morphology	J:177557
	abnormal trabecular bone morphology	J:177557
	decreased body weight	J:177557
	decreased bone resorption	J:177557
	decreased length of long bones	J:177557
	decreased osteoclast cell number	J:177557
	failure of tooth eruption	J:177557
	increased bone volume	J:177557
	increased spleen weight	J:177557
	kyphosis	J:177557
	osteopetrosis	J:177557
	postnatal growth retardation	J:177557
Tnfsf11tm1Pngr/Tnfsf11tm1Pngr involves: 129P2/OlaHsd	abnormal thymus epithelium morphology	J:173115
Tnfsf11tm1Pngr/Tnfsf11tm1Pngr involves: 129P2/OlaHsd * C57BL/6	abnormal immune system morphology	J:52369
	abnormal immune system physiology	J:52369
	abnormal long bone epiphyseal plate morphology	J:52369
	abnormal mammary gland growth during pregnancy	J:64718
	abnormal neurocranium morphology	J:52369
	abnormal pro-B cell differentiation	J:52369
	absent mesenteric lymph nodes	J:52369
	absent peripheral lymph nodes	J:52369
	arrested T cell differentiation	J:52369
	decreased immature B cell number	J:52369
	decreased interferon-gamma secretion	J:52369
	decreased interleukin-2 secretion	J:52369
	decreased interleukin-4 secretion	J:52369
	decreased interleukin-5 secretion	J:52369
	decreased interleukin-6 secretion	J:52369
	decreased length of long bones	J:52369
	decreased mature B cell number	J:52369
	decreased osteoclast cell number	J:52369
	decreased thymus weight	J:52369
	extramedullary hematopoiesis	J:52369
	failure of tooth eruption	J:52369, J:64718
	normal hematopoietic system phenotype	J:52369
	normal homeostasis/metabolism phenotype	J:52369
	normal immune system phenotype	J:52369
	increased bone mineral density	J:52369
	increased diameter of long bones	J:52369
	increased spleen weight	J:52369
	lactation failure	J:64718
	macrocytic anemia	J:52369
	osteopetrosis	J:52369, J:64718
	postnatal growth retardation	J:52369
	round face	J:52369
	small Peyer's patches	J:52369
	thin neurocranium	J:52369
	thymus hypoplasia	J:52369
Tnfsf11tm1Ywc/Tnfsf11+ involves: 129P2/OlaHsd	absent peripheral lymph nodes	J:65888
Tnfsf11tm1Ywc/Tnfsf11tm1Ywc involves: 129P2/OlaHsd	abnormal bone marrow morphology	J:233265
	abnormal cervical lymph node morphology	J:65888
	abnormal chondrocyte differentiation	J:64737
	abnormal chondrocyte morphology	J:64737
	abnormal long bone epiphyseal plate morphology	J:64737
	abnormal long bone epiphyseal plate proliferative zone	J:64737
	abnormal long bone internal diameter	J:233265
	abnormal lung morphology	J:233265
	abnormal pelvic girdle bone morphology	J:64737
	abnormal spleen B cell follicle morphology	J:65888
	abnormal spleen marginal zone morphology	J:65888
	abnormal spleen morphology	J:65888
	abnormal splenic cell ratio	J:233265
	abnormal thymus cell ratio	J:233265
	absent cervical lymph nodes	J:65888
	absent mesenteric lymph nodes	J:65888
	absent peripheral lymph nodes	J:65888
	decreased body weight	J:233265
	decreased bone marrow cell number	J:233265
	decreased bone mineral density	J:233265
	decreased bone trabecula number	J:233265
	decreased circulating calcium level	J:233265
	decreased cranium height	J:64737
	decreased Langerhans cell number	J:137471
	decreased length of long bones	J:64737
	decreased osteoclast cell number	J:64737, J:65888
	decreased Peyer's patch number	J:233265
	decreased spleen white pulp amount	J:233265
	extramedullary hematopoiesis	J:233265
	failure of tooth eruption	J:64737, J:233265
	increased bone mineral density	J:233265
	increased bone mineralization	J:233265
	increased bone volume	J:233265
	increased diameter of tibia	J:64737
	increased long bone epiphyseal plate size	J:64737
	increased spleen red pulp amount	J:233265
	increased trabecular bone thickness	J:233265
	increased width of hypertrophic chondrocyte zone	J:64737
	optic canal stenosis	J:233265
	osteopetrosis	J:233265
	short tibia	J:64737
	short vertebral column	J:64737
	small Peyer's patches	J:233265
	small thymus medulla	J:233265