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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Crebbp
CREB binding protein
MGI:1098280
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdkn1btm1Mlf/Cdkn1b+
Crebbptm1Jvd/Crebbptm1Jvd
Tg(MMTV-cre)4Mam/0
involves: 129 * C57BL/6 * CBA * FVB 		increased T cell derived lymphoma incidence J:88323
Crebbptm1Dli/Crebbp+
Ep300tm1Dli/Ep300+
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		decreased embryo size J:47301
exencephaly J:47301
open neural tube J:47301
prenatal lethality, complete penetrance J:47301
Crebbptm1Jvd/Crebbptm1Jvd
Ep300tm2Pkb/Ep300tm2Pkb
Tg(Lck-cre)548Jxm/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal T cell number J:105505
decreased double-positive T cell number J:105505
increased double-negative T cell number J:105505
Crebbptm2Pkb/Crebbp+
Tg(IghMyc)22Bri/0
involves: 129P2/OlaHsd * C57BL/6 * SJL 		abnormal tumor incidence J:103607
Crebbptm2Pkb/Crebbp+
Ep300tm3Pkb/Ep300+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal craniofacial morphology J:103607
decreased body size J:103607
Crebbptm2Pkb/Crebbp+
Ep300tm3Pkb/Ep300tm3Pkb
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		embryonic lethality during organogenesis, incomplete penetrance J:103607
Crebbptm2Pkb/Crebbptm2Pkb
Ep300tm3Pkb/Ep300tm3Pkb
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		embryonic lethality during organogenesis J:103607
Tg(Camk2a-Crebbp*)1364Tabe/0
involves: C57BL/6 * SJL 		abnormal contextual conditioning behavior J:121812
abnormal spatial learning J:121812
normal behavior/neurological phenotype J:121812
increased thigmotaxis J:121812
reduced long-term potentiation J:121812
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory