Cast Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cast
calpastatin
MGI:1098236

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cast^{tm1.1(KOMP)Vlcg}/Cast^{tm1.1(KOMP)Vlcg} B6N(Cg)-Cast^{tm1.1(KOMP)Vlcg}/2J	decreased fasting circulating glucose level	J:211773
	decreased startle reflex	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating phosphate level	J:211773
	increased circulating sodium level	J:211773
	increased heart weight	J:211773
Cast^tm1Tcs/Cast^tm1Tcs B6.129-Cast^tm1Tcs	increased susceptibility to neuronal excitotoxicity	J:109976
Tg(Myh6-Cast)1Gwd/0 involves: FVB/N	abnormal heart left ventricle morphology	J:133797
	abnormal heart rate	J:133797
	abnormal myocardial fiber morphology	J:133797
	decreased heart rate	J:133797
	decreased physiological sensitivity to xenobiotic	J:133797
	decreased ventricle muscle contractility	J:133797
	dilated cardiomyopathy	J:133797

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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