Pld1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pld1
phospholipase D1
MGI:109585

15 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pld1^tm1.1Gdp/Pld1^tm1.1Gdp involves: 129/SvJ * C57BL/6	abnormal autophagy	J:207283
Pld1^tm1.1Gdp/Pld1^tm1.1Gdp involves: 129/SvJ * C57BL/6	normal homeostasis/metabolism phenotype	J:207283
Pld1^tm1.1Mafr/Pld1^tm1.1Mafr B6.Cg-Pld1^tm1.1Mafr	abnormal platelet physiology	J:193451
	abnormal tumor vascularization	J:193451
	decreased angiogenesis	J:193451
	decreased metastatic potential	J:193451
	decreased tumor growth/size	J:193451
Pld1^tm1.1Mafr/Pld1^tm1.1Mafr Not Specified	no abnormal phenotype detected	J:192844
Pld1^tm3Mafr/Pld1^tm3Mafr B6.129-Pld1^tm3Mafr	abnormal platelet activation	J:216114
Pld1^tm3Mafr/Pld1^tm3Mafr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased cerebral infarct size	J:211547
	decreased platelet aggregation	J:211547
	decreased susceptibility to induced morbidity/mortality	J:211547
	decreased susceptibility to injury	J:211547
	decreased susceptibility to ischemic brain injury	J:211547
	increased mean platelet volume	J:211547

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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