Macf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Macf1
microtubule-actin crosslinking factor 1
MGI:108559

39 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Macf1^tm1Efu/Macf1^tm1Efu involves: 129	abnormal electroretinogram waveform feature	J:240903
	abnormal retina development	J:240903
	retina photoreceptor degeneration	J:240903
	thin retina outer nuclear layer	J:240903
Macf1^tm1Efu/Macf1^tm1Efu Tg(KRT14-cre)1Efu/0 involves: 129	decreased keratinocyte migration	J:143595
	delayed wound healing	J:143595
	increased keratinocyte adhesion	J:143595
Macf1^tm1Efu/Macf1^tm1Efu Tg(rx3-icre)1Mjam/0 involves: 129	abnormal electroretinogram waveform feature	J:240903
	abnormal retina morphology	J:240903
	absent photoreceptor inner segment	J:240903
	absent photoreceptor outer segment	J:240903
	decreased a-wave amplitude	J:240903
	decreased b-wave amplitude	J:240903
	enlarged brain ventricles	J:240903
Macf1^tm1Efu/Macf1^tm1Efu Tg(Six3-cre)69Frty/0 involves: 129 * C57BL/6 * DBA/2	abnormal electroretinogram waveform feature	J:240903
	abnormal photoreceptor connecting cilium morphology	J:240903
	abnormal retina bipolar cell morphology	J:240903
	abnormal retina development	J:240903
	abnormal retina morphology	J:240903
	abnormal retina neuronal layer morphology	J:240903
	abnormal retina photoreceptor layer morphology	J:240903
	absent b-wave	J:240903
	absent photoreceptor inner segment	J:240903
	absent photoreceptor outer segment	J:240903
	decreased a-wave amplitude	J:240903
	decreased b-wave amplitude	J:240903
Macf1^tm1Liem/Macf1^tm1Liem involves: 129S6/SvEvTac * C57BL/6J	absent mesoderm	J:110693
	embryonic growth arrest	J:110693
	embryonic lethality between implantation and somite formation, complete penetrance	J:110693
	failure of primitive streak formation	J:110693
Macf1^tm2.1Liem/Macf1^tm2.2Liem Tg(Nes-cre)1Kln/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	abnormal anterior commissure morphology	J:164146
	abnormal brain morphology	J:164146
	abnormal cerebral cortex morphology	J:164146
	abnormal cerebral hemisphere morphology	J:164146
	abnormal dentate gyrus morphology	J:164146
	abnormal hippocampal commissure morphology	J:164146
	abnormal hippocampus pyramidal cell layer	J:164146
	abnormal lateral ventricle morphology	J:164146
	abnormal neuronal migration	J:164146
	abnormal stratification in cerebral cortex	J:164146
	cyanosis	J:164146
	ectopic hippocampus pyramidal cells	J:164146
	neonatal lethality, complete penetrance	J:164146
	normal nervous system phenotype	J:164146
	respiratory distress	J:164146
	small lateral ventricles	J:164146
	thin cerebral cortex	J:164146

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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