About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptprv
protein tyrosine phosphatase receptor type V
MGI:108027
46 phenotypes from 4 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Amhr2tm3(cre)Bhr/Amhr2+
Ptprvtm1Kry/Ptprvtm1Kry
involves: 129S/SvEv 		normal reproductive system phenotype J:170888
Ptprvtm1Asmi/Ptprv+
involves: 129P2/OlaHsd * MF1 		no abnormal phenotype detected J:89221
Ptprvtm1Asmi/Ptprvtm1Asmi
involves: 129P2/OlaHsd 		abnormal male germ cell apoptosis J:170888
decreased circulating glucose level J:126780
decreased susceptibility to diet-induced obesity J:126780
decreased susceptibility to xenobiotic induced morbidity/mortality J:126780
enlarged testis J:170888
normal growth/size/body region phenotype J:126780
increased circulating testosterone level J:170888
increased epididymis weight J:170888
increased Leydig cell number J:170888
increased seminal vesicle weight J:170888
increased sperm number J:170888
increased testis weight J:170888
normal reproductive system phenotype J:170888
Ptprvtm1Asmi/Ptprvtm1Asmi
involves: 129P2/OlaHsd * C57BL/6J 		decreased circulating glucose level J:152695
increased circulating insulin level J:152695
increased pancreatic beta cell proliferation J:152695
Ptprvtm1b(NCOM)Mfgc/Ptprvtm1b(NCOM)Mfgc
C57BL/6N-Ptprvtm1b(NCOM)Mfgc/Tcp 		decreased circulating potassium level J:211773
decreased prepulse inhibition J:211773
Ptprvtm1Kry/Ptprvtm1Kry
Tg(Col1a1-cre)1Kry/0
involves: FVB 		abnormal glucose homeostasis J:126780
abnormal muscle fiber mitochondrial morphology J:126780
abnormal pancreatic islet morphology J:126780
decreased circulating free fatty acids level J:126780
decreased circulating glucose level J:126780
decreased circulating triglyceride level J:126780
decreased gonadal fat pad weight J:126780
normal growth/size/body region phenotype J:126780
hypoglycemia J:126780
improved glucose tolerance J:126780
increased adipocyte glucose uptake J:126780
increased circulating adiponectin level J:126780
increased circulating insulin level J:126780
increased circulating testosterone level J:170888
increased energy expenditure J:126780
increased epididymis weight J:170888
increased fat cell size J:126780
increased insulin secretion J:126780
increased insulin sensitivity J:126780
increased muscle cell glucose uptake J:126780
increased pancreatic beta cell mass J:126780
increased pancreatic beta cell proliferation J:126780
increased pancreatic islet number J:126780
increased seminal vesicle weight J:170888
increased sperm number J:170888
pancreatic islet hyperplasia J:126780
postnatal lethality, incomplete penetrance J:126780
normal skeleton phenotype J:126780
Tg(Col1a1-Ptprv)1Kry/?
Not Specified 		abnormal glucose homeostasis J:126780
decreased adiponectin level J:126780
decreased circulating insulin level J:126780
decreased insulin secretion J:126780
decreased pancreatic beta cell mass J:126780
decreased pancreatic beta cell proliferation J:126780
hyperglycemia J:126780
impaired glucose tolerance J:126780
insulin resistance J:126780
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory