Nkx3-2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nkx3-2
NK3 homeobox 2
MGI:108015

31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gli3^tm1Alj/Gli3^tm1Alj Nkx3-2^tm1(cre)Wez/Nkx3-2⁺ involves: 129S6/SvEvTac * 129S7/SvEvBrd	normal digestive/alimentary phenotype	J:199664
	normal mortality/aging	J:199664
Gli3^tm1Alj/Gli3^tm1Alj Nkx3-2^tm1(cre)Wez/Nkx3-2⁺ Smo^tm2Amc/Smo^tm2Amc involves: 129S6/SvEvTac * 129S7/SvEvBrd * 129X1/SvJ	abnormal digestive system morphology	J:199664
Gt(ROSA)26Sor^{tm1(Gli2)Jmao}/Gt(ROSA)26Sor⁺ Smo^tm2Amc/Smo^tm2Amc Nkx3-2^tm1(cre)Wez/Nkx3-2⁺ involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ	normal digestive/alimentary phenotype	J:199664
Gt(ROSA)26Sor^{tm1(Gli2)Jmao}/Gt(ROSA)26Sor⁺ Nkx3-2^tm1(cre)Wez/Nkx3-2⁺ involves: 129S7/SvEvBrd	normal digestive/alimentary phenotype	J:199664
Gt(ROSA)26Sor^{tm1(Smo/EYFP)Amc}/Gt(ROSA)26Sor⁺ Nkx3-2^tm1(cre)Wez/Nkx3-2⁺ involves: 129S7/SvEvBrd * 129X1/SvJ	abnormal intestine development	J:199664
Nkx3-2^tm1(cre)Tsa/Nkx3-2⁺ Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa involves: 129S7/SvEvBrd * C57BL/6	abnormal digestive system development	J:98520
	abnormal enteric neuron morphology	J:98520
	abnormal forestomach-glandular stomach junction morphology	J:98520
	abnormal gastric parietal cell morphology	J:98520
	abnormal stomach epithelium morphology	J:98520
	abnormal stomach glandular epithelium morphology	J:98520
	abnormal stomach morphology	J:98520
	abnormal stomach pyloric region morphology	J:98520
	abnormal stomach smooth muscle circular layer morphology	J:98520
	small forestomach	J:98520
	small stomach	J:98520
Nkx3-2^tm1Bobh/Nkx3-2^tm1Bobh Nkx3-1^tm1Hha/Nkx3-1^tm1Hha involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	abnormal axial skeleton morphology	J:79198
	abnormal cartilage development	J:79198
	abnormal cervical atlas morphology	J:79198
	abnormal lumbar vertebrae morphology	J:79198
	abnormal rib morphology	J:79198
	abnormal sclerotome morphology	J:79198
	abnormal vertebrae development	J:79198
	abnormal vertebral body morphology	J:79198
	kinked tail	J:79198
	lethality throughout fetal growth and development, complete penetrance	J:79198
Smo^tm2Amc/Smo^tm2Amc Nkx3-2^tm1(cre)Wez/Nkx3-2⁺ involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ	abnormal enteric neuron morphology	J:199664
	abnormal enterocyte proliferation	J:199664
	abnormal intestinal enteroendocrine cell morphology	J:199664
	abnormal intestinal goblet cell morphology	J:199664
	abnormal intestinal smooth muscle morphology	J:199664
	abnormal intestine development	J:199664
	abnormal intestine physiology	J:199664
	neonatal lethality, complete penetrance	J:199664

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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