Lrig1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrig1
leucine-rich repeats and immunoglobulin-like domains 1
MGI:107935

40 phenotypes from 5 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrig1^{Gt(GST4169C6)Lex}/Lrig1^{Gt(GST4169C6)Lex} B6N.129-Lrig1^{Gt(GST4169C6)Lex}	abnormal auditory brainstem response waveform shape	J:202451
	normal hearing/vestibular/ear phenotype	J:202451
	increased or absent distortion product otoacoustic emission threshold	J:202451
	increased or absent threshold for auditory brainstem response	J:202451
Lrig1^m1Anu/Lrig1^m1Anu C57BL/NCrlAnu-Lrig1^m1Anu	normal immune system phenotype	J:104190
Lrig1^{tm1.1(cre/ERT2)Rjc}/Lrig1^{tm1.1(cre/ERT2)Rjc} involves: 129 * C57BL/6	no abnormal phenotype detected	J:186084
Lrig1^{tm1a(EUCOMM)Wtsi}/Lrig1^{tm1a(EUCOMM)Wtsi} B6Brd;B6Dnk;B6N-Tyr^c-Brd Lrig1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal hair cycle	J:232539
	abnormal hair shedding	J:232539
Lrig1^{tm1a(EUCOMM)Wtsi}/Lrig1^{tm1a(EUCOMM)Wtsi} B6Brd;B6N-Tyr^c-Brd Lrig1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal skin condition	J:232539
	disheveled coat	J:232539
	scaly skin	J:232539
Lrig1^{tm1a(EUCOMM)Wtsi}/Lrig1^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Lrig1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal behavior	J:175295
	abnormal skin condition	J:175295
	abnormal tail morphology	J:175295
	decreased body length	J:165965
	decreased body weight	J:165965
	decreased total body fat amount	J:165965
Lrig1^{tm1a(EUCOMM)Wtsi}/Lrig1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Lrig1^{tm1a(EUCOMM)Wtsi}	abnormal epidermis stratum basale morphology	J:209956
	distorted hair follicle pattern	J:209956
	scaly skin	J:209956
	thick epidermis	J:209956
Lrig1^{tm1a(EUCOMM)Wtsi}/Lrig1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6N	abnormal auditory brainstem response	J:213427
	abnormal hair shedding	J:213427
	abnormal skin adnexa morphology	J:213427
	abnormal skin condition	J:213427
	decreased body weight	J:213427
	decreased bone mineral density	J:213427
	decreased circulating alanine transaminase level	J:213427
	decreased circulating alkaline phosphatase level	J:213427
	decreased circulating aspartate transaminase level	J:213427
	decreased total body fat amount	J:213427
	epidermal hyperplasia	J:213427
	fusion of vertebral arches	J:213427
	hyperkeratosis	J:213427
	increased susceptibility to bacterial infection	J:213427
	normal integument phenotype	J:213427
	scaly skin	J:213427
	vertebral fusion	J:213427
Lrig1^tm1Ita/Lrig1^tm1Ita involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal facial morphology	J:77286
	abnormal keratinocyte differentiation	J:77286
	abnormal skin morphology	J:77286
	alopecia	J:77286
	epidermal hyperplasia	J:77286
	hyperkeratosis	J:77286
	increased keratinocyte proliferation	J:77286
	normal nervous system phenotype	J:77286
	parakeratosis	J:77286
	psoriasis	J:77286
	scaly skin	J:77286
	thick epidermis	J:77286
	thick tail	J:77286

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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