About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp3cb
protein phosphatase 3, catalytic subunit, beta isoform
MGI:107163
29 phenotypes from 7 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ppp3cbM1Btlr/Ppp3cb+
C57BL/6J-Ppp3cbM1Btlr 		abnormal CD4-positive, alpha-beta T cell physiology J:236670
abnormal CD8-positive, alpha-beta T cell physiology J:236670
abnormal NK cell physiology J:236670
increased CD8-positive, alpha-beta memory T cell proliferation J:236670
Ppp3cbM1Btlr/Ppp3cbM1Btlr
C57BL/6J-Ppp3cbM1Btlr 		abnormal CD4-positive, alpha-beta T cell physiology J:236670
abnormal CD8-positive, alpha-beta T cell physiology J:236670
abnormal NK cell physiology J:236670
increased CD8-positive, alpha-beta memory T cell proliferation J:236670
Ppp3cbm2Btlr/Ppp3cb+
C57BL/6J-Ppp3cbm2Btlr 		abnormal CD4-positive, alpha-beta T cell physiology J:236671
abnormal CD8-positive, alpha-beta T cell physiology J:236671
increased CD8-positive, alpha-beta memory T cell proliferation J:236671
Ppp3cbm2Btlr/Ppp3cbm2Btlr
C57BL/6J-Ppp3cbm2Btlr 		abnormal CD4-positive, alpha-beta T cell physiology J:236671
abnormal CD8-positive, alpha-beta T cell physiology J:236671
abnormal NK cell physiology J:236671
decreased response to antigen J:236671
increased CD8-positive, alpha-beta memory T cell proliferation J:236671
Ppp3cbM3Btlr/Ppp3cb+
C57BL/6J-Ppp3cbM3Btlr 		decreased CD8-positive, alpha-beta memory T cell number J:254889
increased central memory CD4-positive, alpha-beta T cell number J:254889
Ppp3cbM3Btlr/Ppp3cbM3Btlr
C57BL/6J-Ppp3cbM3Btlr 		decreased CD8-positive, alpha-beta memory T cell number J:254889
decreased CD8-positive, naive alpha-beta T cell number J:254889
increased central memory CD4-positive, alpha-beta T cell number J:254889
increased central memory CD8 positive, alpha-beta T cell number J:254889
Ppp3cbM4Btlr/Ppp3cb+
C57BL/6J-Ppp3cbM4Btlr 		decreased CD8-positive, alpha-beta memory T cell number J:254905
increased central memory CD8 positive, alpha-beta T cell number J:254905
Ppp3cbM4Btlr/Ppp3cbM4Btlr
C57BL/6J-Ppp3cbM4Btlr 		decreased CD8-positive, alpha-beta memory T cell number J:254905
increased central memory CD8 positive, alpha-beta T cell number J:254905
Ppp3cbm5Btlr/Ppp3cbm5Btlr
C57BL/6J-Ppp3cbm5Btlr 		abnormal T cell morphology J:272839
decreased CD8-positive, alpha-beta T cell number J:272839
Ppp3cbM6Btlr/Ppp3cbM6Btlr
C57BL/6J-Ppp3cbM6Btlr 		abnormal lymphocyte morphology J:272840
decreased alpha-beta T cell number J:272840
decreased CD4-positive, alpha-beta T cell number J:272840
decreased CD8-positive, alpha-beta T cell number J:272840
Ppp3cbtm1Jmk/Ppp3cbtm1Jmk
involves: 129S6/SvEvTac 		abnormal cytokine secretion J:109586
abnormal skeletal muscle fiber type ratio J:110822
decreased body weight J:110822
decreased skeletal muscle fiber diameter J:110822
decreased susceptibility to injury J:109586
decreased T cell proliferation J:109586
increased skeletal muscle fiber number J:110822
Ppp3cbtm1Jmk/Ppp3cbtm1Jmk
involves: 129S6/SvEvTac * C57BL/6 		abnormal T cell differentiation J:77729
normal cardiovascular system phenotype J:75775
decreased body weight J:75775
decreased response of heart to induced stress J:75775
decreased single-positive T cell number J:77729
decreased T cell number J:77729
decreased T cell proliferation J:77729
decreased thymus weight J:75775
small heart J:75775
thymus hypoplasia J:77729
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory