42 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Egln1tm1.1Brei/Egln1tm1.1Brei Hif1atm3Rsjo/Hif1atm3Rsjo Tg(CD68-icre)1Bwlx/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	domed cranium	J:194598
	normal hematopoietic system phenotype	J:194598
	hydrocephaly	J:194598
	increased hematocrit	J:194598
	postnatal lethality	J:194598
Egln1tm1.1Fsl/Egln1+ Hif1atm3.1Rsjo/Hif1a+ B6.Cg-Egln1tm1.1Fsl Hif1atm3.1Rsjo	increased hematocrit	J:202737
Egln1tm2.1Fsl/Egln1tm2.1Fsl Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ Hif1atm3Rsjo/Hif1atm3Rsjo B6.Cg-Gt(ROSA)26Sortm9(cre/ESR1)Arte Egln1tm2.1Fsl Hif1atm3Rsjo	extramedullary hematopoiesis	J:202737
	increased erythropoietin level	J:202737
	increased hematocrit	J:202737
	increased spleen weight	J:202737
	premature death	J:202737
Egln2tm1Pec/Egln2tm1Pec Hif1atm1Pec/Hif1a+ involves: 129S/SvEv * Swiss	normal muscle phenotype	J:132630
Egln3tm1Pjr/Egln3tm1Pjr Hif1atm1Pec/Hif1a+ involves: 129S/SvEv * Swiss	abnormal neuron physiology	J:136034
	abnormal superior cervical ganglion morphology	J:136034
Epas1tm1Mcs/Epas1tm1Mcs Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S1/Sv * 129X1/SvJ * CD-1	decreased erythroid progenitor cell number	J:186085
	decreased trabecular bone volume	J:186085
	normal hematopoietic system phenotype	J:186085
Epas1tm1Mcs/Epas1tm1Mcs Hif1atm3Rsjo/Hif1atm3Rsjo Vhltm1Jae/Vhltm1Jae Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * CD-1	decreased bone trabecula number	J:186085
	decreased circulating erythropoietin level	J:186085
	decreased trabecular bone volume	J:186085
	normal hematopoietic system phenotype	J:186085
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sor+ Hif1atm3Rsjo/Hif1atm3Rsjo Tg(tetO-cre)LC1Bjd/0 involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae * 129X1/SvJ	abnormal cell migration	J:130751
Hif1atm1.1Mcs/Hif1a+ involves: 129S6/SvEvTac	abnormal embryo development	J:105812
	hemorrhage	J:105812
	pericardial effusion	J:105812
	prenatal lethality, incomplete penetrance	J:105812
Hif1atm1.1Mcs/Hif1atm1.1Mcs involves: 129S6/SvEvTac	abnormal developmental patterning	J:105812
	abnormal embryo development	J:105812
	abnormal embryonic epiblast morphology	J:105812
	embryonic growth arrest	J:105812
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:105812
Hif1atm1Rsjo/Hif1atm1Rsjo Hif1antm1.2Rsjo/Hif1antm1.2Rsjo involves: 129S1/Sv * 129X1/SvJ	normal cellular phenotype	J:160941
	decreased cell proliferation	J:160941
Hif1atm1Rsjo/Hif1atm1Rsjo Hif1antm1.2Rsjo/Hif1antm1.2Rsjo Vhltm1Jae/Vhltm1Jae involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	normal cellular phenotype	J:160941
Hif1atm2Mcs/Hif1atm2Mcs Not Specified	no abnormal phenotype detected	J:105812
Hif1atm3Rsjo/Hif1atm3Rsjo Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ Hprt1tm1(Pck1-cre)Vhh/Y involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ	abnormal cell differentiation	J:130751
	decreased susceptibility to injury	J:130751
	kidney inflammation	J:130751
	renal fibrosis	J:130751
Hif1atm3Rsjo/Hif1atm3Rsjo Hprt1tm1(Pck1-cre)Vhh/Y Vhltm1Jae/Vhltm1Jae involves: 129 * BALB/c * C57BL/6	abnormal kidney morphology	J:106705
	abnormal kidney vasculature morphology	J:106705
	abnormal vasodilation	J:97652
	hepatic steatosis	J:97652
	increased hemoglobin content	J:97652
	increased hepatic hemangioma incidence	J:97652
	increased vascular endothelial cell number	J:97652
	kidney cyst	J:106705
	kidney inflammation	J:106705
	polycythemia	J:97652
Hif1atm3Rsjo/Hif1atm3Rsjo Vhltm1Jae/Vhltm1Jae Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129 * BALB/c * C57BL/6 * DBA	abnormal vasodilation	J:97652
	hepatic steatosis	J:97652
	increased vascular endothelial cell number	J:97652
Hif1atm3Rsjo/Hif1atm3Rsjo Vhltm1Jae/Vhltm1Jae Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * CD-1	increased circulating erythropoietin level	J:186085
	increased hematocrit	J:186085