Epcam Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Epcam
epithelial cell adhesion molecule
MGI:106653

38 phenotypes from 6 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Epcam^{Gt(RST412)Byg}/Epcam^{Gt(RST412)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal colon morphology	J:195002
	abnormal crypts of Lieberkuhn morphology	J:195002
	abnormal enterocyte morphology	J:195002
	abnormal intestinal epithelium morphology	J:195002
	abnormal intestinal mucosa morphology	J:195002
	abnormal intestine morphology	J:195002
	abnormal intestine physiology	J:195002
	internal hemorrhage	J:195002
	postnatal growth retardation	J:195002
	postnatal lethality, complete penetrance	J:195002
	slow postnatal weight gain	J:195002
Epcam^{Gt(RST556)Byg}/Epcam^{Gt(RST556)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal neural tube closure	J:155941
	abnormal placenta labyrinth morphology	J:155941
	abnormal thrombosis	J:155941
	decreased embryo size	J:155941
	decreased trophoblast giant cell number	J:155941
	delayed neural tube closure	J:155941
	embryonic growth arrest	J:155941
	embryonic lethality during organogenesis, complete penetrance	J:155941
	small placenta	J:155941
Epcam^tm1.1Mcu/Epcam^tm1.1Mcu Tg(CD207-cre)1Dhka/0 involves: 129 * C57BL/6 * C57BL/6J * SJL/J	abnormal cell migration	J:182665
	abnormal Langerhans cell morphology	J:182665
	abnormal Langerhans cell physiology	J:182665
	increased susceptibility to type IV hypersensitivity reaction	J:182665
Epcam^tm1.2Hmd/Epcam^tm1.2Hmd involves: 129 * C57BL/6	abnormal intestine physiology	J:190580
Epcam^tm1.2Hmd/Epcam^tm1.2Hmd involves: 129 * C57BL/6	lethality during fetal growth through weaning, incomplete penetrance	J:190580
Epcam^tm1.2Msiv/Epcam^tm1.2Msiv involves: C57BL/6 * FVB/N * SJL	abnormal duodenum morphology	J:210901
	abnormal enterocyte physiology	J:210901
	abnormal enterocyte proliferation	J:210901
	abnormal ileum morphology	J:210901
	abnormal intestine morphology	J:210901
	abnormal intestine physiology	J:210901
	abnormal jejunum morphology	J:210901
	normal behavior/neurological phenotype	J:210901
	blunted small intestinal villi	J:210901
	decreased body size	J:210901
	intestinal edema	J:210901
	lethargy	J:210901
	postnatal growth retardation	J:210901
	postnatal lethality, complete penetrance	J:210901
	small intestinal inflammation	J:210901
Epcam^tm1Hmd/Epcam^tm1Hmd involves: 129 * C57BL/6	abnormal intestinal mucosa morphology	J:190580
	diarrhea	J:190580
	intestinal hemorrhage	J:190580
	lethality during fetal growth through weaning, incomplete penetrance	J:190580
	postnatal growth retardation	J:190580

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23