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Gene trapped Allele Detail
Symbol: EpcamGt(RST412)Byg
Name: epithelial cell adhesion molecule; gene trap RST412, BayGenomics
MGI ID: MGI:4127340
Gene: Epcam  Location: Chr17:87943407-87958555 bp, + strand  Genetic Position: Chr17, 57.87 cM
Alliance: EpcamGt(RST412)Byg page
Tufting enteropathy in EpcamGt(RST412)Byg/EpcamGt(RST412)Byg mice

Show the 4 phenotype image(s) involving this allele.

Mutant Cell Line:  RST412
Germline Transmission:  Earliest citation of germline transmission: J:195002
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1TMpfs     Vector Type: secretory trap
Mutation detailsThe gene trap cassette inserted into intron 3. Expression of the fusion transcript is seen in the intestines of heterozygous mice. (J:195002)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Scheme for the generation of the EpcamGt(RST412)Byg and EpcamGt(RST413)Byg alleles
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epcam Mutation:  26 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory