Ilrun Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ilrun
inflammation and lipid regulator with UBA-like and NBR1-like domains
MGI:106281

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ilrun^em1(IMPC)Tcp/Ilrun^em1(IMPC)Tcp C57BL/6NCrl-Ilrun^em1(IMPC)Tcp/Tcp	abnormal skin morphology	J:211773
	decreased lean body mass	J:211773
	impaired glucose tolerance	J:211773
Ilrun^{tm1a(KOMP)Wtsi}/Ilrun^{tm1a(KOMP)Wtsi} involves: C57BL/6N	abnormal apolipoprotein level	J:302091
	abnormal cholesterol homeostasis	J:302091
	abnormal circulating apolipoprotein level	J:302091
	abnormal circulating non-HDL cholesterol level	J:302091
	abnormal lipid metabolism	J:302091
	abnormal liver physiology	J:302091
	decreased body weight	J:302091
	decreased circulating cholesterol level	J:302091
	decreased circulating HDL cholesterol level	J:302091
	decreased circulating LDL cholesterol level	J:302091
	decreased circulating phospholipid level	J:302091
	decreased circulating triglyceride level	J:302091
	decreased circulating VLDL triglyceride level	J:302091
	decreased insulin secretion	J:302091
	decreased lipogenesis	J:302091
	decreased liver cholesterol level	J:302091
	decreased liver triglyceride level	J:302091
	decreased liver weight	J:302091
	normal homeostasis/metabolism phenotype	J:302091
	impaired glucose tolerance	J:302091

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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