St8sia2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
MGI:106020

25 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
St8sia2^tm1Jxm/St8sia2^tm1Jxm St8sia4^tm1.1Mifu/St8sia4^tm1.1Mifu involves: C57BL/6	abnormal astrocyte morphology	J:126687
	abnormal brain interneuron morphology	J:126687
	abnormal brain morphology	J:126687
	abnormal cerebral cortex morphology	J:126687
	abnormal CNS glial cell morphology	J:126687
	abnormal corpus callosum morphology	J:126687
	abnormal diencephalon morphology	J:126687
	abnormal lateral ventricle morphology	J:126687
	abnormal motor capabilities/coordination/movement	J:126687
	abnormal neuron differentiation	J:126687
	abnormal neuronal migration	J:126687
	abnormal postnatal subventricular zone morphology	J:126687
	abnormal rostral migratory stream morphology	J:126687
	decreased body size	J:126687
	decreased cerebral cortex pyramidal cell number	J:126687
	decreased striatum size	J:126687
	dilated lateral ventricle	J:126687
	ectopic cerebral cortex pyramidal cells	J:126687
	increased neuron apoptosis	J:126687
	loss of hippocampal neurons	J:126687
	postnatal lethality, complete penetrance	J:126687
	small cerebellum	J:126687
	small olfactory bulb	J:126687
	thin cerebral cortex	J:126687
St8sia2^tm1Jxm/St8sia2^tm1Jxm St8sia4^tm1.1Mifu/St8sia4^tm1.1Mifu Tg(Thy1-YFP)HJrs/? involves: C57BL/6 * CBA	abnormal cerebral cortex pyramidal cell morphology	J:126687
	decreased cerebral cortex pyramidal cell number	J:126687

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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