Ppox Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppox
protoporphyrinogen oxidase
MGI:104968

25 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppox^em1(IMPC)J/Ppox⁺ C57BL/6NJ-Ppox^em1(IMPC)J/Mmjax	abnormal auditory brainstem response	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating phosphate level	J:211773
Ppox^em1(IMPC)J/Ppox^em1(IMPC)J C57BL/6NJ-Ppox^em1(IMPC)J/Mmjax	abnormal allantois morphology	J:374598
	abnormal chorioallantoic fusion	J:374598
	abnormal embryo morphology	J:374598
	abnormal embryo size	J:211773
	abnormal head shape	J:374598
	abnormal heart development	J:374598
	abnormal placenta development	J:374598
	abnormal placenta labyrinth morphology	J:374598
	abnormal trophoblast layer morphology	J:374598
	decreased embryo size	J:374598
	decreased spongiotrophoblast size	J:374598
	embryonic growth retardation	J:211773, J:374598
	embryonic lethality during organogenesis, complete penetrance	J:374598
	embryonic lethality prior to tooth bud stage	J:211773
	failure of initiation of embryo turning	J:374598
	incomplete rostral neuropore closure	J:374598
	kinked neural tube	J:374598
	preweaning lethality, complete penetrance	J:211773
Ppox^tm1.1Had/Ppox⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal enzyme/coenzyme activity	J:226160
	abnormal feces composition	J:226160
	abnormal urine homeostasis	J:226160
Ppox^tm1Had/Ppox⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal enzyme/coenzyme activity	J:226160
	abnormal feces composition	J:226160
	abnormal urine homeostasis	J:226160
Ppox^tm1Had/Ppox^tm1Had involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	prenatal lethality, complete penetrance	J:226160

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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