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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hes5
hes family bHLH transcription factor 5
MGI:104876
33 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Fgu/Hes1tm1Hojo
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal neurohypophysis morphology J:121843
abnormal pituitary diverticulum morphology J:121843
abnormal pituitary gland development J:121843
abnormal pituitary gland morphology J:121843
abnormal pituitary infundibular stalk morphology J:121843
absent pituitary intermediate lobe J:121843
increased somatotroph cell number J:121843
pituitary gland hypoplasia J:121843
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Kag/Hes1tm1Kag
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal brain morphology J:139170
abnormal embryonic neuroepithelium morphology J:139170
abnormal neuron differentiation J:139170
absent choroid plexus J:139170
increased Cajal-Retzius cell number J:139170
Hes1tm1Fgu/Hes1+
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129S1/Sv * 129X1/SvJ * CD-1 		increased cochlear outer hair cell number J:70081
Hes1tm1Fgu/Hes1tm1Fgu
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129S1/Sv * 129X1/SvJ * CD-1 		premature neuronal precursor differentiation J:94391
Hes1tm1Fgu/Hes1tm1Fgu
Hes5tm1Fgu/Hes5+
involves: 129S1/Sv * 129X1/SvJ * CD-1 		increased cochlear inner hair cell number J:70081
Hes1tm1Fgu/Hes1tm1Fgu
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129S1/Sv * 129X1/SvJ 		abnormal choroid plexus morphology J:139170
Hes1tm1Fgu/Hes1tm1Fgu
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal astrocyte morphology J:94391
abnormal brain development J:94391
abnormal CNS glial cell morphology J:94391
abnormal dorsal root ganglion morphology J:94391
abnormal embryonic/fetal subventricular zone morphology J:94391
abnormal ependyma morphology J:94391
abnormal forebrain morphology J:94391
abnormal nasal placode morphology J:62024
abnormal neural tube morphology J:62024, J:94391
abnormal spinal cord morphology J:94391
absent oligodendrocytes J:94391
absent optic vesicle J:94391
decreased embryo size J:54662
embryonic lethality during organogenesis, incomplete penetrance J:94391
neuron hypertrophy J:54662
premature neuronal precursor differentiation J:94391
Hes1tm1Kag/Hes1tm1Kag
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
Tg(Nes-cre/ERT2)5-1Imayo/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		normal nervous system phenotype J:139170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory