Penk-rs Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Penk-rs
preproenkephalin, related sequence
MGI:104628

19 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Penk-rs^tm1Pig/Penk-rs^tm1Pig B6.129-Penk-rs^tm1Pig	abnormal T-helper 2 physiology	J:62435
	decreased behavioral withdrawal response	J:66732
	decreased chemically-elicited antinociception	J:66732
	decreased physiological sensitivity to xenobiotic	J:66732
	decreased T-helper 2 cell number	J:62435
	lung inflammation	J:62435
Penk-rs^tm1Pig/Penk-rs^tm1Pig B6.129-Penk-rs^tm1Pig/J	abnormal associative learning	J:98226
	normal behavior/neurological phenotype	J:107954
	decreased behavioral withdrawal response	J:98226
	decreased chemically-elicited antinociception	J:98226
	decreased physiological sensitivity to xenobiotic	J:98226
	impaired behavioral response to nicotine	J:98226
Penk-rs^tm1Pig/Penk-rs^tm1Pig involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal chemical nociception	J:35826
	abnormal emotion/affect behavior	J:35826
	abnormal touch/ nociception	J:35826
	decreased exploration in new environment	J:35826
	decreased thermal nociceptive threshold	J:35826
	increased aggression towards humans	J:35826
	increased aggression towards mice	J:35826
	increased anxiety-related response	J:35826
	increased thigmotaxis	J:35826
	normal reproductive system phenotype	J:35826

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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