Penk-rs Other Genome Feature Detail

Summary

• Symbol
  Penk-rs
• Name
  preproenkephalin, related sequence
• Synonyms
  Penk, Penk2

• Feature Type
  unclassified other genome feature
• IDs
  MGI:104628
  NCBI Gene: 110182

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 9, Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  19 phenotypes from 1 allele in 3 genetic backgrounds
  27 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  3 strains or lines available
• Comparison Matrix
  Gene Expression + Phenotype

Homozygous null mice display increased anxiety-like behaviors, increased aggression, abnormal chemical and thermal nociception, abnormal nicotine and THC responses, and abnormal Th2-dependent inflammatory responses.

Expression

• Assay Results
  2
• Tissues
  1
• Literature Summary
  1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Sequences &
Gene Models

• NCBI Gene
  110182

Molecular
Reagents

• All nucleic 11

  Genomic 2

  cDNA 7

  Primer pair 1

  Other 1

Other
Accession IDs

MGD-MRK-13229, MGD-MRK-26065

References

• Summaries
  All 42

  Developmental Gene Expression 1

  Phenotypes 27
• Earliest
  J:8253 Zurawski G, et al., Activation of mouse T-helper cells induces abundant preproenkephalin mRNA synthesis. Science. 1986 May 9;232(4751):772-5
• Latest
  J:346538 Puri C, et al., Pre-proenkephalin 1 is Downregulated Under Unloading and is Involved in Osteoblast Biology. Calcif Tissue Int. 2024 Mar 20;