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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dst
dystonin
MGI:104627
96 phenotypes from 23 alleles in 27 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Dstdt-23J/Dstdt-23J
Not Specified
axonal dystrophy J:11718
Dstdt-23Rbrc/Dstdt-23Rbrc
involves: C3H/HeN * C57BL/6
abnormal brainstem morphology J:251779
abnormal locomotor activation J:251779
abnormal muscle physiology J:251779
abnormal neuron morphology J:251779
abnormal posture J:251779
abnormal sensory neuron morphology J:251779
abnormal spinal cord morphology J:251779
abnormal spinal nerve morphology J:251779
axonal spheroids J:251779
decreased locomotor activity J:251779
decreased myelin sheath thickness J:251779
dystonia J:251779
impaired limb coordination J:251779
impaired righting response J:251779
muscular atrophy J:251779
neurodegeneration J:251779
premature death J:251779
slow postnatal weight gain J:251779
Dstdt-24J/Dstdt-24J
involves: C57BL/6
axonal dystrophy J:11718
Dstdt-27J/Dst+
B10.PL/(73NS)Sn-Dstdt-27J/J
abnormal axon morphology J:48174
abnormal myelination J:48174
abnormal Schwann cell morphology J:48174
Dstdt-27J/Dstdt-27J
B10.PL/(73NS)Sn-Dstdt-27J/J
abnormal axon morphology J:48174, J:91505
abnormal axonal transport J:91505
abnormal dorsal root ganglion morphology J:91505
abnormal dorsal spinal root morphology J:47356, J:91495
abnormal myelin sheath morphology J:48174
abnormal myelination J:48174
abnormal nervous system physiology J:91505
abnormal Schwann cell morphology J:48174
abnormal sciatic nerve morphology J:91505
abnormal sensory neuron morphology J:47356
abnormal somatic nervous system morphology J:91505
axon degeneration J:91495, J:91505
demyelination J:48174, J:91495, J:91505
peripheral nervous system degeneration J:47356
Dstdt-30J/Dstdt-30J
C57BL/6J-Dstdt-30J/J
dystonia J:155853
neurodegeneration J:155853
premature death J:155853
Dstdt-31J/Dstdt-31J
involves: DBA/1LacJ
dystonia J:155854
premature death J:155854
Dstdt-32J/Dstdt-32J
involves: 129S/Sv * 129S2/SvPas
abnormal somatic nervous system morphology J:51014
fecal incontinence J:51014
limb grasping J:51014
postnatal lethality J:51014
urinary incontinence J:51014
Dstdt-33J/Dstdt-33J
129S1/Sv
ataxia J:61053
impaired coordination J:61053
postnatal lethality, complete penetrance J:61053
seizures J:61053
Dstdt-35J/Dstdt-35J
involves: 129S4/SvJae * C57BL/6
abnormal motor capabilities/coordination/movement J:115254
Dstdt-36J/Dstdt-36J
C57BL/6J-Dstdt-36J/J
abnormal posture J:82238
Dstdt-37J/Dstdt-37J
C57BL/6J-Dstdt-37J/J
axonal dystrophy J:82238
chromatolysis J:82238
decreased body size J:82238
decreased bone marrow cell number J:82238
decreased skeletal muscle fiber size J:82238
demyelination J:82238
dystonia J:82238
impaired righting response J:82238
Dstdt-38J/Dstdt-38J
involves: BALB/cByJ * C57BL/6J
abnormal posture J:82238
decreased body size J:82238
muscle spasm J:82238
normal reproductive system phenotype J:82238
weakness J:82238
Dstdt-39J/Dstdt-39J
involves: NOD
abnormal motor coordination/balance J:157224
cachexia J:157224
dystonia J:157224
Dstdt-alb/Dstdt-alb
BALB/cByJ-Dstdt-alb
abnormal nervous system morphology J:64441
abnormal neuron morphology J:6316
dystonia J:64441
Dstdt-J/Dstdt-J
B6C3Fe a/a-Dstdt-J/J
abnormal eye distance/ position J:106403
abnormal motor coordination/balance J:106403
abnormal postural reflex J:106403
abnormal posture J:106403
abnormal response to tactile stimuli J:106403
abnormal skin pigmentation J:106403
ataxia J:106403
decreased aggression J:106403
decreased body weight J:106403
decreased startle reflex J:106403
enophthalmos J:106403
impaired balance J:106403
impaired coordination J:106403
positive geotaxis J:106403
tremors J:106403
Dstdt-J/Dstdt-J
C3HeB/FeJ-Dstdt-J
abnormal motor coordination/balance J:24773
abnormal posture J:24773
athetotic walking movements J:24773
postnatal lethality, complete penetrance J:24773
Dstdt/Dstdt
involves: C57BL/6 * Q
demyelination J:6491
Dstdt/Dstdt
involves: Q
dystonia J:5674
impaired limb coordination J:5674
limb grasping J:5674
neurodegeneration J:5674
premature death J:5674
Dstdt/Dstdt
Q-Dstdt
abnormal nervous system morphology J:5330
axonal dystrophy J:5330
dystonia J:64095
gliosis J:5330
neurodegeneration J:5330
paresis J:64095
premature death J:64095
DstGt(E182H05)Wrst/DstGt(E182H05)Wrst
B6NCrj.129P2-DstGt(E182H05)Wrst
abnormal brainstem morphology J:251779
abnormal neuron morphology J:251779
abnormal neuron physiology J:228781
abnormal posture J:251779
abnormal spinal cord morphology J:251779
abnormal trigeminal motor nucleus morphology J:228781
axon degeneration J:228781
axonal spheroids J:251779
decreased brain size J:228781
decreased myelin sheath thickness J:228781
demyelination J:228781
dystonia J:228781, J:251779
impaired limb coordination J:228781
neurodegeneration J:228781, J:251779
premature death J:228781
small dorsal root ganglion J:228781
DstGt(E182H05)Wrst/DstGt(E182H05)Wrst
involves: 129P2/OlaHsd * ICR
abnormal muscle electrophysiology J:228781, J:251779
Dstm1Btlr/Dstm1Btlr
C57BL/6J-Dstm1Btlr
ataxia J:218961
decreased body weight J:218961
Dstm2Btlr/Dstm2Btlr
C57BL/6J-Dstm2Btlr
normal behavior/neurological phenotype J:218962
head tilt J:218962
stereotypic behavior J:218962
Dstm3Btlr/Dstm3Btlr
C57BL/6J-Dstm3Btlr
ataxia J:218968
impaired limb coordination J:218968
DstTg4/Dst+
involves: CD-1
abnormal axon morphology J:48174
abnormal myelination J:48174
abnormal Schwann cell morphology J:48174
DstTg4/DstTg4
involves: C57BL/6 * CD-1
abnormal axon morphology J:209161
abnormal dorsal root ganglion morphology J:209161
abnormal gait J:209161
abnormal muscle spindle morphology J:209161
abnormal neuromuscular synapse morphology J:209161
abnormal sensory neuron morphology J:209161
axon degeneration J:209161
blepharoptosis J:209161
conjunctivitis J:209161
impaired coordination J:209161
limb grasping J:209161
neuron degeneration J:209161
postnatal lethality J:209161
slow postnatal weight gain J:209161
small dorsal root ganglion J:209161
DstTg4/DstTg4
involves: CD-1
abnormal axon morphology J:48174
abnormal circumvallate papillae morphology J:104592
abnormal dorsal root ganglion morphology J:91495
abnormal dorsal spinal root morphology J:17844, J:47356
abnormal glossopharyngeal ganglion morphology J:104592
abnormal gustatory papilla taste bud morphology J:104592
abnormal muscle physiology J:55704
abnormal myelin sheath morphology J:48174
abnormal myelination J:17844, J:48174
abnormal nervous system physiology J:48174
abnormal Schwann cell morphology J:48174
abnormal sensory neuron morphology J:47356
abnormal skeletal muscle fiber mitochondrial morphology J:55704
abnormal skeletal muscle fiber morphology J:55704
abnormal vagus nerve morphology J:104592
abnormal Z line morphology J:55704
impaired limb coordination J:17844
impaired skeletal muscle contractility J:55704
muscle weakness J:55704
peripheral nervous system degeneration J:47356
postnatal lethality J:17844
Dsttm1b(EUCOMM)Wtsi/Dst+
C57BL/6N-Dsttm1b(EUCOMM)Wtsi/Bay
abnormal embryo size J:211773
persistence of hyaloid vascular system J:211773
unresponsive to tactile stimuli J:211773
Dsttm1b(EUCOMM)Wtsi/Dsttm1b(EUCOMM)Wtsi
C57BL/6N-Dsttm1b(EUCOMM)Wtsi/Bay
preweaning lethality, incomplete penetrance J:211773
unresponsive to tactile stimuli J:211773
Dsttm1Efu/Dsttm1Efu
involves: C57BL/6
abnormal myelin sheath morphology J:24974
alopecia J:24974
axon degeneration J:24974
blistering J:24974
delayed wound healing J:24974
dystonia J:24974
impaired righting response J:24974
kinked tail J:24974
muscular atrophy J:24974
premature death J:24974

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory