62 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Acvr2atm1Hsch/Acvr2a+ Acvr2btm1Enl/Acvr2btm1Enl involves: 129S1/Sv * 129S4/SvJae * C57BL/6J	perinatal lethality, complete penetrance	J:57262
Acvr2atm1Hsch/Acvr2a+ Bmpr2tm1.1Enl/Bmpr2tm1.1Enl Tg(KRT14-cre)1Ipc/0 involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * SJL	abnormal auchene hair morphology	J:189569
	abnormal awl hair morphology	J:189569
	abnormal coat/ hair morphology	J:189569
	abnormal hair cycle	J:189569
	abnormal hair cycle catagen phase	J:189569
	abnormal hair follicle outer root sheath morphology	J:189569
	abnormal hair follicle regression	J:189569
	abnormal hair growth	J:189569
	abnormal hair medulla	J:189569
	abnormal hair medullary septa cells	J:189569
	abnormal hair shaft melanin granule distribution	J:189569
	abnormal hair shaft morphology	J:189569
	abnormal zigzag hair morphology	J:189569
	absent hair club	J:189569
	alopecia	J:189569
	early exit from anagen phase	J:189569
	early exit from telogen phase	J:189569
	increased curvature of awl hairs	J:189569
	increased curvature of guard hairs	J:189569
	increased hair follicle cell proliferation	J:189569
	long nails	J:189569
	premature hair regrowth	J:189569
	striated fur	J:189569
	thick epidermis	J:189569
	thin hair shaft	J:189569
Acvr2atm1Hsch/Acvr2a+ Acvr2btm1Spo/Acvr2btm1Spo involves: 129S1/Sv * 129S4/SvJae	abnormal left-right axis patterning	J:114533
	lumbar vertebral transformation	J:114533
	right pulmonary isomerism	J:114533
	transposition of great arteries	J:114533
Acvr2atm1Hsch/Acvr2a+ Acvr2btm1.1Spo/Acvr2btm1.1Spo involves: 129S1/Sv * 129S4/SvJae * FVB/N	abnormal left-right axis patterning	J:114533
	lumbar vertebral transformation	J:114533
	right pulmonary isomerism	J:114533
	transposition of great arteries	J:114533
Acvr2atm1Hsch/Acvr2atm1Hsch Acvr2btm1.1Spo/Acvr2btm1.1Spo involves: 129S1/Sv * 129S4/SvJae * FVB/N	abnormal embryonic tissue morphology	J:114533
	embryonic growth arrest	J:114533
	embryonic lethality between somite formation and embryo turning	J:114533
	embryonic-extraembryonic boundary constriction	J:114533
Acvr2atm1Hsch/Acvr2atm1Hsch Acvr2btm1Enl/Acvr2b+ involves: 129S1/Sv * 129S4/SvJae * C57BL/6J	abnormal gastrulation	J:57262
	abnormal mesoderm development	J:57262
	abnormal primitive streak elongation	J:57262
	abnormal rostral-caudal axis patterning	J:57262
	absent allantois	J:57262
	absent amnion	J:57262
	absent head fold	J:57262
	absent heart tube	J:57262
	embryonic growth arrest	J:57262
	embryonic lethality between implantation and somite formation, complete penetrance	J:57262
	embryonic-extraembryonic boundary constriction	J:57262
Acvr2atm1Hsch/Acvr2atm1Hsch Acvr2btm1Enl/Acvr2btm1Enl involves: 129S1/Sv * 129S4/SvJae * C57BL/6J	absent mesoderm	J:57262
	embryonic growth arrest	J:57262
	embryonic lethality between implantation and somite formation, complete penetrance	J:57262
	embryonic-extraembryonic boundary constriction	J:57262
	failure to gastrulate	J:57262
	increased embryonic epiblast cell apoptosis	J:57262
Acvr2atm1Hsch/Acvr2atm1Hsch Bmpr2tm1.1Enl/Bmpr2tm1.1Enl Tg(KRT14-cre)1Ipc/0 involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * SJL	abnormal hair follicle development	J:189569
	abnormal hair growth	J:189569
	abnormal vibrissa follicle morphology	J:189569
	absent hair follicle bulb	J:189569
	absent vibrissae	J:189569
	eyelids open at birth	J:189569
	perinatal lethality, complete penetrance	J:189569
	underdeveloped hair follicles	J:189569
Acvr2atm1Hsch/Acvr2atm1Hsch Bmpr2tm1.1Enl/Bmpr2tm1.1Enl Tg(Tyr-cre)1Lru/Y involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * DBA/2	abnormal coat/hair pigmentation	J:189569
	abnormal hair follicle melanin granule morphology	J:189569
	diluted coat color	J:189569
	reduced hair shaft melanin granule number	J:189569
	small melanosome	J:189569
Acvr2atm1Hsch/Acvr2atm1Hsch Bmpr2tm1.1Enl/Bmpr2tm1.1Enl Tg(Tyr-cre)1Lru/0 involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * DBA/2	mosaic coat color	J:189569
Acvr2atm1Hsch/Acvr2atm1Hsch Nodaltm1Rob/Nodal+ involves: 129S/SvEv * 129S1/Sv * C57BL/6J	abnormal gastrulation	J:57262
	abnormal head morphology	J:57262
	cyclopia	J:57262
	decreased forebrain size	J:57262
	embryonic lethality, complete penetrance	J:57262