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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tbx4
T-box 4
MGI:102556
41 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tbx4tm1(cre)Tmj/Tbx4tm1(cre)Tmj
Not Specified
no abnormal phenotype detected J:177135
Tbx4tm1.1Kng/Tbx4+
involves: 129P2/OlaHsd * C57BL/6J * DBA/2
abnormal patella morphology J:139169
abnormal pelvic girdle bone morphology J:139169
brachydactyly J:139169
short femur J:139169
short tibia J:139169
Tbx4tm1.1Kng/Tbx4tm1.1Kng
involves: 129P2/OlaHsd * C57BL/6J * DBA/2
abnormal fibula morphology J:139169
abnormal limb development J:139169
abnormal patella morphology J:139169
abnormal pelvic girdle bone morphology J:139169
brachydactyly J:139169
fused tarsal bones J:139169
normal limbs/digits/tail phenotype J:139169
patellar dislocation J:139169
short femur J:139169
short tibia J:139169
Tbx4tm1.1Pa/Tbx4+
involves: 129S1/Sv * 129X1/SvJ
delayed allantois development J:83256
delayed chorioallantoic fusion J:83256
Tbx4tm1.1Pa/Tbx4tm1.1Pa
involves: 129S1/Sv * 129X1/SvJ
abnormal allantois morphology J:83256
abnormal umbilical artery morphology J:83256
abnormal vascular regression J:83256
absent umbilical cord J:83256
delayed allantois development J:83256
distended pericardium J:83256
embryonic lethality during organogenesis, complete penetrance J:83256
failure of chorioallantoic fusion J:83256
hemorrhage J:83256
increased allantois apoptosis J:83256
pericardial edema J:83256
small allantois J:83256
small hindlimb buds J:83256
Tbx4tm1.1Pa/Tbx4tm1.2Pa
Tg(Prrx1-cre)1Cjt/0
involves: 129 * C57BL/6J * FVB/N * SJL/J
abnormal hindlimb morphology J:117423
abnormal ischium morphology J:117423
abnormal pelvic girdle bone morphology J:117423
brachydactyly J:117423
fused phalanges J:117423
fused tarsal bones J:117423
short femur J:117423
short fibula J:117423
Tbx4tm1.2Pa/Tbx4tm1.2Pa
involves: 129S1/Sv * 129X1/SvJ * FVB/N
no abnormal phenotype detected J:117423
Tbx4tm1.2Pa/Tbx4tm1.2Pa
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N
abnormal autopod morphology J:117423
abnormal digit morphology J:117423
abnormal limb bud morphology J:117423
abnormal metatarsal bone morphology J:117423
abnormal pelvic girdle bone morphology J:117423
absent femur J:117423
embryonic lethality during organogenesis, complete penetrance J:117423
embryonic lethality during organogenesis, incomplete penetrance J:117423
failure of chorioallantoic fusion J:117423
fused phalanges J:117423
hindlimb oligodactyly J:117423
normal limbs/digits/tail phenotype J:117423
short femur J:117423
short fibula J:117423
short hindlimb J:117423
Tbx4tm1.2Pa/Tbx4tm1.2Pa
Tg(Prrx1-cre/ERT2)1Mlgn/0
involves: 129S1/Sv * 129X1/SvJ
abnormal hindlimb morphology J:157917
abnormal limb development J:157917
Tbx4tm1Pa/Tbx4+
involves: 129S1/Sv * 129X1/SvJ
delayed allantois development J:83256
delayed chorioallantoic fusion J:83256
Tbx4tm1Pa/Tbx4tm1Pa
involves: 129S1/Sv * 129X1/SvJ
abnormal allantois morphology J:83256
abnormal umbilical artery morphology J:83256
abnormal vascular regression J:83256
absent umbilical cord J:83256
delayed allantois development J:83256
distended pericardium J:83256
embryonic lethality during organogenesis, complete penetrance J:83256
failure of chorioallantoic fusion J:83256
hemorrhage J:83256
increased allantois apoptosis J:83256
pericardial edema J:83256
small allantois J:83256
small hindlimb buds J:83256
Tbx4tm4b(EUCOMM)Wtsi/Tbx4tm4b(EUCOMM)Wtsi
C57BL/6N-Tbx4tm4b(EUCOMM)Wtsi/Ucd
abnormal embryo size J:211773
embryonic lethality prior to tooth bud stage J:211773
pale yolk sac J:211773
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory