Tbx4^tm1(cre)Tmj
Targeted Allele Detail

Summary

• Symbol: Tbx4^tm1(cre)Tmj
• Name: T-box 4; targeted mutation 1, Thomas M Jessell
• MGI ID: MGI:5292375
• Synonyms: Tbx4^cre
• Gene: Tbx4 Location: Chr11:85777248-85806923 bp, + strand Genetic Position: Chr11, 51.42 cM
• Alliance: Tbx4^tm1(cre)Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176643
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Tbx4^tm1(cre)Tmj expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tbx4 (MGI:102556)

• An IRES-cre-pA PGK-neo cassette was inserted into the Nhe site of the 3' UTR. (J:176643)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx4 (mouse) Summary of all recombinase alleles driven by Tbx4. Alliance mouse Tbx4 gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx4 Mutation: 23 strains or lines available

References

• Original: J:176643 Luria V, et al., Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron. 2008 Dec 26;60(6):1039-53
• All: 10 reference(s)