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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tbx4tm1(cre)Tmj
targeted mutation 1, Thomas M Jessell
MGI:5292375
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tbx4tm1(cre)Tmj/Tbx4tm1(cre)Tmj Not Specified MGI:5298079
cn2
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Rilm/Robo2tm1Rilm
Tbx4tm1(cre)Tmj/Tbx4+
involves: 129 MGI:5522804
cn3
Efnb2tm1Henk/Efnb2tm1Henk
Tbx4tm1(cre)Tmj/Tbx4+
involves: 129S1/Sv * 129X1/SvJ MGI:5298191


Genotype
MGI:5298079
hm1
Allelic
Composition
Tbx4tm1(cre)Tmj/Tbx4tm1(cre)Tmj
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbx4tm1(cre)Tmj mutation (0 available); any Tbx4 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable and fertile




Genotype
MGI:5522804
cn2
Allelic
Composition
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Rilm/Robo2tm1Rilm
Tbx4tm1(cre)Tmj/Tbx4+
Genetic
Background
involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo1tm1Matl mutation (2 available); any Robo1 mutation (87 available)
Robo2tm1Rilm mutation (1 available); any Robo2 mutation (101 available)
Tbx4tm1(cre)Tmj mutation (0 available); any Tbx4 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• normal lung and diaphragm morphology and normal lung inflation




Genotype
MGI:5298191
cn3
Allelic
Composition
Efnb2tm1Henk/Efnb2tm1Henk
Tbx4tm1(cre)Tmj/Tbx4+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm1Henk mutation (0 available); any Efnb2 mutation (28 available)
Tbx4tm1(cre)Tmj mutation (0 available); any Tbx4 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice exhibit normal motor neuron specification and initial phases of motor axon extension





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory