About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cdk5r1
cyclin dependent kinase 5, regulatory subunit 1
MGI:101764
44 phenotypes from 5 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cdk5r1tm1Ivi/Cdk5r1tm1Ivi
B6.Cg-Cdk5r1tm1Ivi
abnormal cerebellum morphology J:86345
abnormal stratification in cerebral cortex J:86345
delaminated Purkinje cell layer J:86345
ectopic cerebellar granule cells J:86345
Cdk5r1tm1Lht/Cdk5r1tm1Lht
involves: 129S4/SvJae
abnormal axon extension J:193542
abnormal behavioral response to xenobiotic J:204269
abnormal cerebellar molecular layer J:38857
abnormal cerebral cortex morphology J:38857
abnormal dentate gyrus morphology J:38857
abnormal forebrain development J:38857
abnormal forebrain morphology J:38857
abnormal hippocampus layer morphology J:38857
abnormal hippocampus morphology J:38857
abnormal innervation J:204269
abnormal olfactory bulb development J:38857
abnormal physiological response to xenobiotic J:204269
abnormal sensitization to xenobiotic J:204269
abnormal stratification in cerebral cortex J:204269
abnormal striatum morphology J:38857
decreased corpus callosum size J:38857, J:204269
dilated lateral ventricle J:38857
ectopic Purkinje cell J:38857
hyperactivity J:204269
increased cellular glucose import J:204269
increased serotonin level J:204269
premature death J:38857
reduced long-term potentiation J:193542
seizures J:38857
Cdk5r1tm1Lht/Cdk5r1tm1Lht
involves: 129S4/SvJae * C57BL/6
abnormal cerebellar molecular layer J:38857
abnormal cerebral cortex morphology J:38857, J:71181
abnormal cerebral cortex pyramidal cell morphology J:38857
abnormal dentate gyrus morphology J:38857
abnormal forebrain morphology J:38857
abnormal hippocampus layer morphology J:38857
abnormal hippocampus morphology J:38857, J:71181
abnormal olfactory bulb development J:38857
abnormal subplate morphology J:71181
decreased corpus callosum size J:38857
decreased striatum size J:38857
dilated lateral ventricle J:38857
ectopic Purkinje cell J:38857
increased susceptibility to pharmacologically induced seizures J:38857
premature death J:38857
seizures J:38857
thin cortical plate J:38857
Cdk5r1tm1Ohsh/Cdk5r1tm1Ohsh
involves: 129 * C57BL/6J
abnormal hippocampus granule cell morphology J:100692
abnormal hippocampus pyramidal cell morphology J:100692
abnormal spatial learning J:100692
impaired coordination J:215344
reduced long-term depression J:100692
Cdk5r1tm1Ohsh/Cdk5r1tm1Ohsh
Not Specified
increased thermal nociceptive threshold J:105661
Cdk5r1tm2.1Lht/Cdk5r1tm2.1Lht
B6.129-Cdk5r1tm2.1Lht
abnormal excitatory postsynaptic potential J:208030
abnormal long-term depression J:208030
slow extinction of fear memory J:208030
Cdk5r1tm2Ohsh/Cdk5r1tm2Ohsh
Tg(Pcp2-cre)1Amc/0
involves: C57BL/6 * C57BL/6N
absent long-term depression J:215344
impaired coordination J:215344
impaired synaptic plasticity J:215344
normal nervous system phenotype J:215344
reduced long-term potentiation J:215344

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory